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|Title:||The medial prefrontal cortex and memory of cue location in the rat||Contributor(s):||Rawson, Timothy (author); O'Kane, Michael (author); Talk, Andrew (author)||Publication Date:||2010||DOI:||10.1016/j.nlm.2009.09.003||Handle Link:||https://hdl.handle.net/1959.11/7497||Abstract:||We developed a single-trial cue-location memory task in which rats experienced an auditory cue while exploring an environment. They then recalled and avoided the sound origination point after the cue was paired with shock in a separate context. Subjects with medial prefrontal cortical (mPFC) lesions made no such avoidance response, but both lesioned and control subjects avoided the cue itself when presented at test. A follow up assessment revealed no spatial learning impairment in either group. These findings suggest that the rodent mPFC is required for incidental learning or recollection of the location at which a discrete cue occurred, but is not required for cue recognition or for allocentric spatial memory.||Publication Type:||Journal Article||Source of Publication:||Neurobiology of Learning and Memory, 93(1), p. 132-136||Publisher:||Academic Press||Place of Publication:||United States of America||ISSN:||1074-7427
|Field of Research (FOR):||170101 Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology)||Socio-Economic Objective (SEO):||920410 Mental Health||Peer Reviewed:||Yes||HERDC Category Description:||C1 Refereed Article in a Scholarly Journal||Statistics to Oct 2018:||Visitors: 264
|Appears in Collections:||Journal Article|
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