Joining the dots: neurobiological links in a functional analysis of depression

Title
Joining the dots: neurobiological links in a functional analysis of depression
Publication Date
2010
Author(s)
Sharpley, Chris
( author )
OrcID: https://orcid.org/0000-0001-7922-4848
Email: csharpl3@une.edu.au
UNE Id une-id:csharpl3
Bitsika, Vicki
Type of document
Journal Article
Language
en
Entity Type
Publication
Publisher
BioMed Central Ltd
Place of publication
United Kingdom
DOI
10.1186/1744-9081-6-73
UNE publication id
une:7483
Abstract
Depression is one of the major contributors to the Total Disease Burden and afflicts about one-sixth of Western populations. One of the most effective treatments for depression focuses upon analysis of causal chains in overt behaviour, but does not include brain-related phenomena as steps along these causal pathways. Recent research findings regarding the neurobiological concomitants of depressive behaviour suggest a sequence of structural and functional alterations to the brain which may also produce a beneficial outcome for the depressed individual--that of adaptive withdrawal from uncontrollable aversive stressors. Linking these brain-based explanations to models of observable contingencies for depressive behaviour can provide a comprehensive explanation of how depressive behaviour occurs and why it persists in many patients.
Link
Citation
Behavioral and Brain Functions, v.6
ISSN
1744-9081

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