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Title: Joining the dots: neurobiological links in a functional analysis of depression
Contributor(s): Sharpley, Chris  (author)orcid ; Bitsika, Vicki  (author)
Publication Date: 2010
DOI: 10.1186/1744-9081-6-73
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Abstract: Depression is one of the major contributors to the Total Disease Burden and afflicts about one-sixth of Western populations. One of the most effective treatments for depression focuses upon analysis of causal chains in overt behaviour, but does not include brain-related phenomena as steps along these causal pathways. Recent research findings regarding the neurobiological concomitants of depressive behaviour suggest a sequence of structural and functional alterations to the brain which may also produce a beneficial outcome for the depressed individual--that of adaptive withdrawal from uncontrollable aversive stressors. Linking these brain-based explanations to models of observable contingencies for depressive behaviour can provide a comprehensive explanation of how depressive behaviour occurs and why it persists in many patients.
Publication Type: Journal Article
Source of Publication: Behavioral and Brain Functions, v.6
Publisher: BioMed Central Ltd
Place of Publication: United Kingdom
ISSN: 1744-9081
Field of Research (FOR): 110319 Psychiatry (incl Psychotherapy)
Socio-Economic Outcome Codes: 920111 Nervous System and Disorders
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
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