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https://hdl.handle.net/1959.11/7191
Title: | Bending over Backwards: Better Estimates of Genetic Covariance Matrices by Penalized REML | Contributor(s): | Meyer, Karin (author); Kirkpatrick, M (author) | Publication Date: | 2010 | Handle Link: | https://hdl.handle.net/1959.11/7191 | Abstract: | Knowledge of genetic parameters and variances is an essential pre-requisite for tasks such as the design of selection programmes or prediction of breeding values. Reliable estimation of these quantities is thus paramount. There is a growing trend to consider more and more complex phenotypes, necessitating multivariate analyses comprising numerous traits. Problems inherent in such analyses, arising from sampling variation and the resulting over-dispersion of sample eigenvalues, are well known. There has been longstanding interest in the 'regularization' of estimated covariance matrices. Generally, this involves a compromise between additional bias and reduced sampling variation of 'improved' estimators. Numerous simulation studies have demonstrated that this can improve the agreement between estimated and population covariance matrices; see Meyer and Kirkpatrick (2010) for a review. For instance, estimators of covariance matrices have been suggested which counter-act upwards bias of the largest and downwards bias of the smallest eigenvalues by shrinking them towards their mean. In quantitative genetic analyses, we attempt to partition covariances into their genetic and environmental components. | Publication Type: | Conference Publication | Conference Details: | WCGALP 2010: 9th World Congress on Genetics Applied to Livestock Production, Leipzig, Germany, 1-6 August, 2010 | Source of Publication: | Proceedings of the 9th World Congress on Genetics Applied to Livestock Production | Publisher: | German Society for Animal Science | Place of Publication: | Germany | Fields of Research (FoR) 2008: | 060412 Quantitative Genetics (incl Disease and Trait Mapping Genetics) 070201 Animal Breeding |
Socio-Economic Objective (SEO) 2008: | 830301 Beef Cattle | Peer Reviewed: | Yes | HERDC Category Description: | E1 Refereed Scholarly Conference Publication | Publisher/associated links: | http://www.wcgalp2010.org/ http://www.kongressband.de/wcgalp2010/assets/html/0061.htm |
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Appears in Collections: | Animal Genetics and Breeding Unit (AGBU) Conference Publication |
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