A quantitative trait locus for faecal worm egg and blood eosinophil counts on chromosome 23 in Australian goats

Title
A quantitative trait locus for faecal worm egg and blood eosinophil counts on chromosome 23 in Australian goats
Publication Date
2010
Author(s)
Bolormaa, S
Van Der Werf, Julius H
( author )
OrcID: https://orcid.org/0000-0003-2512-1696
Email: jvanderw@une.edu.au
UNE Id une-id:jvanderw
Walkden-Brown, Steve W
( author )
OrcID: https://orcid.org/0000-0002-0638-5533
Email: swalkden@une.edu.au
UNE Id une-id:swalkden
Marshall, K L
Ruvinsky, Anatoly
Type of document
Journal Article
Language
en
Entity Type
Publication
Publisher
Blackwell Verlag GmbH
Place of publication
Germany
DOI
10.1111/j.1439-0388.2009.00824.x
UNE publication id
une:6451
Abstract
Three microsatellite markers on goat chromosome 23 adjacent to the MHC were used to test for quantitative trait loci (QTL) affecting faecal worm egg count (WEC) and leukocyte traits in ten Australian Angora and twelve Australian Cashmere half-sib families (n = 16–57 per family). Data were collected from 280 Angora and 347 Cashmere kids over a 3- and 4-year period. A putative QTL affecting trichostrongyle WEC was found in two small families at the 5% chromosome-wise threshold level. The biggest QTL effect for WEC of 1.65 standard deviations (σp) was found within the region of 'OarCP73-BM1258'. A significant QTL affecting blood eosinophil counts at the 1% chromosome–wise threshold level was detected at marker 'BM1258' (at 26 cM) in two Angora and Cashmere families. The magnitude of the putative QTL was 0.69 and 0.85 σp in Angora and Cashmere families, respectively. Due to the comparatively low power of the study these findings should be viewed as indicative rather than definitive.
Link
Citation
Journal of Animal Breeding and Genetics, 127(3), p. 207-214
ISSN
1439-0388
0931-2668
Start page
207
End page
214

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