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Title: Plasmablast Recruitment to the Ruminant Mammary Gland
Contributor(s): Hine, Bradley Charles (author); Glover, Stephen  (supervisor)orcid ; Colditz, Ian  (supervisor)
Conferred Date: 2008
Copyright Date: 2008
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Abstract: Antibodies derived from ruminant mammary secretion can be used prophylactically to protect humans against disease. Although ruminant colostrum is a rich source of antibodies, colostrum is produced only for a short time, whereas milk, which is produced over extended periods, contains extremely low concentrations of antibodies. Therefore the aim of this project was to investigate underlying biological principles that could be employed to develop strategies aimed at enhancing antibody levels in ruminant milk while maintaining normal milk production. To address this aim, it was proposed that increasing the numbers of antibody secreting cells (ASCs) resident in the mammary gland during the lactation period would lead to enhanced local antibody production and in turn increased amounts of antibody in milk.
Publication Type: Thesis Doctoral
Field of Research Codes: 060603 Animal Physiology - Systems
Socio-Economic Outcome Codes: 920108 Immune System and Allergy
Rights Statement: Copyright 2008 - Bradley Charles Hine
Open Access Embargo: 2012-05-25
HERDC Category Description: T2 Thesis - Doctorate by Research
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Appears in Collections:School of Science and Technology
Thesis Doctoral

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