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|Title:||Plasmablast Recruitment to the Ruminant Mammary Gland||Contributor(s):||Hine, Bradley Charles (author); Glover, Stephen (supervisor) ; Colditz, Ian (supervisor)||Conferred Date:||2008||Copyright Date:||2008||Handle Link:||https://hdl.handle.net/1959.11/6259||Abstract:||Antibodies derived from ruminant mammary secretion can be used prophylactically to protect humans against disease. Although ruminant colostrum is a rich source of antibodies, colostrum is produced only for a short time, whereas milk, which is produced over extended periods, contains extremely low concentrations of antibodies. Therefore the aim of this project was to investigate underlying biological principles that could be employed to develop strategies aimed at enhancing antibody levels in ruminant milk while maintaining normal milk production. To address this aim, it was proposed that increasing the numbers of antibody secreting cells (ASCs) resident in the mammary gland during the lactation period would lead to enhanced local antibody production and in turn increased amounts of antibody in milk.||Publication Type:||Thesis Doctoral||Field of Research Codes:||060603 Animal Physiology - Systems||Socio-Economic Outcome Codes:||920108 Immune System and Allergy||Rights Statement:||Copyright 2008 - Bradley Charles Hine||Open Access Embargo:||2012-05-25||HERDC Category Description:||T2 Thesis - Doctorate by Research||Statistics to Oct 2018:||Visitors: 108
|Appears in Collections:||School of Science and Technology|
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