Paoin, Kanawat

Ueda, Kayo

Ingviya, Thammasin

Buya, Suhaimee

Phosri, Arthit

Seposo, Xerxes Tesoro

Seubsman, Sam-ang

Kelly, Matthew

Sleigh, Adrain

Honda, Akiko

Takano, Hirohisa

Chokhanapitak, Jaruwan

Churewong, Chaiyun

Hounthasarn, Suttanit

Khamman, Suwanee

Pandee, Daoruang

Pangsap, Suttinan

Prapamontol, Tippawan

Puengson, Janya

Rimpeekool, Wimalin

Sangrattanakul, Yodyiam

Seubsman, Sam-ang

Somboonsook, Boonchai

Sripaiboonkij, Nintita

Somsamai, Pathumvadee

Tawatsupa, Benjawan

Tangmunkongvorakul, Arunrat

Vilainerun, Duangkae

Wimonwattanaphan, Wanee

Bain, Chris

Banks, Emily

Banwell, Cathy

Berecki-Gisolf, Janneke

Caldwell, Bruce

Carmichael, Gordon

Dellora, Tarie

Dixon, Jane

Friel, Sharon

Harley, David

Jordan, Susan

Kelly, Matthew

Kjellstrom, Tord

Lim, Lynette

McClure, Roderick

McMichael, Anthony

Mark, Tanya

Sleigh, Adrian

Strazdins, Lyndall

Tran, Tam

Yiengprugsawan, Vasoontara

Zhao, Jiaying

2021

<p><i>Background:</i> Several studies have shown the health effects of air pollutants, especially in China, North American and Western European countries. But longitudinal cohort studies focused on health effects of long-term air pollution exposure are still limited in Southeast Asian countries where sources of air pollution, weather conditions, and demographic characteristics are different. The present study examined the association between longterm exposure to air pollution and self-reported morbidities in participants of the Thai cohort study (TCS) in Bangkok metropolitan region (BMR), Thailand.</p> <p><i>Methods:</i> This longitudinal cohort study was conducted for 9 years from 2005 to 2013. Self-reported morbidities in this study included high blood pressure, high blood cholesterol, and diabetes. Air pollution data were obtained from the Thai government Pollution Control Department (PCD). Particles with diameters ≤10 μm (PM₁₀), sulfur dioxide (SO₂), nitrogen dioxide (NO₂), ozone (O₃), and carbon monoxide (CO) exposures were estimated with ordinary kriging method using 22 background and 7 traffic monitoring stations in BMR during 2005–2013. Longterm exposure periods to air pollution for each subject was averaged as the same period of person-time. Cox proportional hazards models were used to examine the association between long-term air pollution exposure with self-reported high blood pressure, high blood cholesterol, diabetes. Results of self-reported morbidity were presented as hazard ratios (HRs) per interquartile range (IQR) increase in PM₁₀, O₃, NO₂, SO₂, and CO.</p> <p><i>Results:</i> After controlling for potential confounders, we found that an IQR increase in PM₁₀ was significantly associated with self-reported high blood pressure (HR = 1.13, 95% CI: 1.04, 1.23) and high blood cholesterol (HR = 1.07, 95%CI: 1.02, 1.12), but not with diabetes (HR = 1.05, 95%CI: 0.91, 1.21). SO₂ was also positively associated with self-reported high blood pressure (HR = 1.22, 95%CI: 1.08, 1.38), high blood cholesterol (HR = 1.20, 95%CI: 1.11, 1.30), and diabetes (HR = 1.21, 95%CI: 0.92, 1.60). Moreover, we observed a positive association between CO and self-reported high blood pressure (HR = 1.07, 95%CI: 1.00, 1.15), but not for other diseases. However, self-reported morbidities were not associated with O₃ and NO₂.</p> <p><i>Conclusions:</i> Long-term exposure to air pollution, especially for PM₁₀ and SO₂ was associated with self-reported high blood pressure, high blood cholesterol, and diabetes in subjects of TCS. Our study supports that exposure to air pollution increases cardiovascular disease risk factors for younger population.</p>

Environmental Research, v.192, p. 1-10

1096-0953

0013-9351

https://hdl.handle.net/1959.11/62542

Academic Press

Attribution 4.0 International

Long-term air pollution exposure and self-reported morbidity: A longitudinal analysis from the Thai cohort study (TCS)

Journal Article

Publication