This chapter presents a description of Set of Experience Knowledge Structure (SOEKS) and Decisional DNA (DDNA), argumentation for a knowledge representation, composition, configuration and metrics. SOEKS is a combination of filtered and amalgamated information obtained from formal decision events. It facilitates effective explicit representation of decisional experience taken from different technologies. SOEKS comprises variables, functions, constraints and rules associated in a DNA shape, allowing the construction of enterprises’ fingerprints called Decisional DNA. SOEKS possesses characteristics that potentialize it as a more precise knowledge representation in a world guided by sensitive dependence and uncertainty, that is, SOEKS is a suitable representation for decisional explicit knowledge that has been gifted with capabilities to manage uncertainty, preciseness and incompleteness. Furthermore, SOEKS extends into the so-called DDNA due to the characterization and aggrupation of SOEKS into different classes termed decisional chromosomes. Such decisional chromosomes simulate specialized genes that when placed together create the decisional experience of an enterprise, the Decisional DNA.