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https://hdl.handle.net/1959.11/5997
Title: | An Initial Exploration of 'in vivo' Hair Cortisol Responses to a Brief Pain Stressor: Latency, Localization and Independence Effects | Contributor(s): | Sharpley, Christopher (author) ; Kauter, Kathleen (author); McFarlane, James R (author) | Publication Date: | 2009 | Handle Link: | https://hdl.handle.net/1959.11/5997 | Abstract: | Cortisol is secreted by the central hypothalamo-pituitary-adrenal axis and affects many target organs and tissues, particularly in response to stressor demands and infection. Recent data reporting cortisol synthesis in hair follicles have shown the existence of a parallel "peripheral" HPA-axis. However, although there is evidence from 'in vitro' studies and single-observation comparisons between groups that cortisol from hair follicles reflects endocrine changes associated with stressor demands, there are no reports to date of repeated measurements of 'in vivo' cortisol responsivity in hair to transitory stressors. This issue was investigated with three males who underwent 1 min cold pressor test (CP). Cortisol response in hair to stressor demand appears to be (a) swift but transitory, (b) localized to the site of the demand and (c) independent of central HPA-axis activity. | Publication Type: | Journal Article | Source of Publication: | Physiological Research, 58(5), p. 757-761 | Publisher: | Akademie Ved Ceske Republiky, Fyziologicky Ustav, Czech Academy of Sciences, Institute of Physiology | Place of Publication: | Czech Republic | ISSN: | 1802-9973 0862-8408 |
Fields of Research (FoR) 2008: | 060699 Physiology not elsewhere classified 060604 Comparative Physiology 060101 Analytical Biochemistry |
Socio-Economic Objective (SEO) 2008: | 970106 Expanding Knowledge in the Biological Sciences | Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal | Publisher/associated links: | http://www.biomed.cas.cz/physiolres/2009/5_09.htm http://www.biomed.cas.cz/physiolres/pdf/58/58_757.pdf |
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Appears in Collections: | Journal Article |
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