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Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/56122
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dc.contributor.authorMoghaddar, Nen
dc.contributor.authorSwan, A Aen
dc.contributor.authorVan Der Werf, J H Jen
local.source.editorEditor(s): Hatcher, Sueen
dc.date.accessioned2023-09-20T00:58:25Z-
dc.date.available2023-09-20T00:58:25Z-
dc.date.issued2023-07-26-
dc.identifier.citationProceedings of the Association for the Advancement of Animal Breeding and Genetics, v.25, p. 270-273en
dc.identifier.issn1328-3227en
dc.identifier.urihttps://hdl.handle.net/1959.11/56122-
dc.description.abstract<p>The objective of this study was to perform a multi-trait meta-analysis of summary statistics of a single-trait genome-wide association study (GWAS) on 10 body weight, carcase composition and eating quality traits in Australian sheep. Meta-analysis was performed based on an approximate chisquared test according to estimated SNP effects and their associated standard errors obtained in a single-trait GWAS. Single-trait association testing was based on single-marker regression analysis in linear mixed models using imputed whole genome sequence data and between 2,707 and 135,022 adjusted phenotypes across the traits studied. Meta-analysis showed higher power of QTL detection compared to single trait GWAS, it confirmed the highly significant QTL regions in single-trait GWAS and revealed numerous pleiotropic QTLs on chromosomes 1, 3, 6, 8, 11, 16 and 18, affecting two or more traits. In total meta-analysis showed 4,823 SNPs in strong association with at least one trait (<i>-Log P≥6.0</i>) but did not show any new highly significant QTL regions across the traits. </p>en
dc.languageenen
dc.publisherAssociation for the Advancement of Animal Breeding and Genetics (AAABG)en
dc.relation.ispartofProceedings of the Association for the Advancement of Animal Breeding and Geneticsen
dc.titleMulti-trait genome wide association meta-analysis of body weight, carcase composition and eating quality traits in Australian sheepen
dc.typeConference Publicationen
dc.relation.conferenceThe 25th Conference of the Association for the Advancement of Animal Breeding and Genetics (AAABG)en
dcterms.accessRightsGolden
local.contributor.firstnameNen
local.contributor.firstnameA Aen
local.contributor.firstnameJ H Jen
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.schoolAnimal Genetics and Breeding Uniten
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.emailnmoghad4@une.edu.auen
local.profile.emailaswan@une.edu.auen
local.profile.emailjvanderw@une.edu.auen
local.output.categoryE1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.date.conference26-28th July, 2023en
local.conference.placePerth, Australiaen
local.publisher.placeArmidale, Australiaen
local.format.startpage270en
local.format.endpage273en
local.url.openhttp://www.aaabg.org/aaabghome/AAABG25papers/66Moghaddar25270.pdfen
local.peerreviewedYesen
local.identifier.volume25en
local.access.fulltextYesen
local.contributor.lastnameMoghaddaren
local.contributor.lastnameSwanen
local.contributor.lastnameVan Der Werfen
dc.identifier.staffune-id:nmoghad4en
dc.identifier.staffune-id:aswanen
dc.identifier.staffune-id:jvanderwen
local.profile.orcid0000-0002-3600-7752en
local.profile.orcid0000-0001-8048-3169en
local.profile.orcid0000-0003-2512-1696en
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:1959.11/56122en
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
local.title.maintitleMulti-trait genome wide association meta-analysis of body weight, carcase composition and eating quality traits in Australian sheepen
local.relation.fundingsourcenoteThis research was partly funded by Meat Livestock Australia project L.GEN.1815.en
local.output.categorydescriptionE1 Refereed Scholarly Conference Publicationen
local.relation.urlhttp://www.aaabg.org/aaabghome/proceedings25.phpen
local.conference.detailsThe 25th Conference of the Association for the Advancement of Animal Breeding and Genetics (AAABG), Perth, Australia, 26-28th July, 2023en
local.search.authorMoghaddar, Nen
local.search.authorSwan, A Aen
local.search.authorVan Der Werf, J H Jen
local.uneassociationYesen
dc.date.presented2023-07-27-
local.atsiresearchNoen
local.conference.venueThe University Club of Western Australiaen
local.sensitive.culturalNoen
local.year.published2023en
local.year.presented2023en
local.fileurl.closedpublishedhttps://rune.une.edu.au/web/retrieve/74a58d42-5ef3-4e96-b17d-57b66e8d71b5en
local.subject.for2020300305 Animal reproduction and breedingen
local.subject.seo2020100412 Sheep for meaten
local.date.start2023-07-26-
local.date.end2023-07-28-
local.profile.affiliationtypeUNE Affiliationen
local.profile.affiliationtypeUNE Affiliationen
local.profile.affiliationtypeUNE Affiliationen
Appears in Collections:Animal Genetics and Breeding Unit (AGBU)
Conference Publication
School of Environmental and Rural Science
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