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Title: Psychological Depression and Cardiac Surgery: A Comprehensive Review
Contributor(s): Tully, Phillip  (author)orcid 
Publication Date: 2012-12-15
Open Access: Yes
DOI: 10.1051/ject/201244224
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The psychological and neurological impact of cardiac surgery has been of keen empirical interest for more than two decades although reports showing the prognostic influence of depression on adverse outcomes lag behind the evidence documented in heart failure, myocardial infarction, and unstable angina. The paucity of research to date is surprising considering that some pathophysiological mechanisms through which depression is hypothesized to affect coronary heart disease (e.g., platelet activation, the inflammatory system, dysrhythmias) are known to be substantially influenced by the use of cardiopulmonary bypass. As such, cardiac surgery may provide a suitable exemplar to better understand the psychiatric mechanisms of cardiopathogenesis. The extant literature is comprehensively reviewed with respect to the deleterious impact of depression on cardiac and neuropsychological morbidity and mortality. Research to date indicates that depression and major depressive episodes increase major cardiovascular morbidity risk after cardiac surgery. The association between depressive disorders and incident delirium is of particular relevance to cardiac surgery staff. Contemporary treatment intervention studies are also described along with suggestions for future cardiac surgery research.

Publication Type: Journal Article
Source of Publication: Journal of Extra-Corporeal Technology, 44(4), p. 224-232
Publisher: American Society of ExtraCorporeal Technology, Inc
Place of Publication: United States of America
ISSN: 2969-8960
Fields of Research (FoR) 2020: 520399 Clinical and health psychology not elsewhere classified
Socio-Economic Objective (SEO) 2020: 200199 Clinical health not elsewhere classified
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
Appears in Collections:Journal Article
School of Psychology

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