Genome wide association study and heritability estimates for ram semen traits

Author(s)
Hodge, H J
De las Heras-Saldana, S
Rindfleish, S J
Stephen, C P
Pant, S D
Publication Date
2023-07-26
Abstract
<p>Ram semen traits influence conception outcomes, which in turn, may influence reproductive efficiency in sheep. As such, this study aimed to estimate genetic parameters and identify Quantitative Trait Loci (QTLs) associated with ram semen traits including volume (VOL), gross motility (GM), concentration (CONC), and percentage post thaw motility (PPTM) in a resource population consisting of five sheep breeds common to Australia. Over 11,000 semen collection records were used to estimate the heritability of semen traits (h<sup>2</sup> = 0.081–0.170). Genome-wide association (GWA) analysis was subsequently performed using a subset of genotyped animals with 5,363 semen collection records. A total of 34 QTLs located on 16 chromosomes were found to be significantly associated with semen traits. Several candidate genes that have previously been linked to male fertility were identified within these QTLs.</p>
Citation
Proceedings of the Association for the Advancement of Animal Breeding and Genetics, v.25, p. 282-285
ISSN
1328-3227
Link
Publisher
Association for the Advancement of Animal Breeding and Genetics (AAABG)
Title
Genome wide association study and heritability estimates for ram semen traits
Type of document
Conference Publication
Entity Type
Publication

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