A genome-wide scan for signatures of selection in Hanwoo and Angus cattle using whole-genome sequence data

Author(s)
Kim, H J
de las Heras-Saldana, S
Clark, S
Van Der Werf, J H J
Publication Date
2022
Abstract
Signature of selection in livestock is a method used to identify genomic regions and candidate genes related to economic traits when phenotypic information is unknown. This study used 406 beef cattle (203 Hanwoo and 203 Angus) with a whole-genome sequence to find selection signatures. As a result, we identified 298 significant genomic regions within Hanwoo, including the candidate genes such as <i>LPL</i> related to the lipid metabolism and 33 genomic regions within Angus with <i>HK1</i> and <i>ACTC1</i> genes linked with glucose metabolism and muscle formation. From the between populations results, 36 significant genomic regions were detected, including the <i>CCKBR</i> gene associated with the feed efficiency. This study can assist in understanding the history of these breeds and identifying the genomic regions under selection for breeding programs in beef cattle.
Citation
Proceedings of 12th World Congress on Genetics Applied to Livestock Production (WCGALP), p. 2632-2635
ISBN
9789086869404
Link
Language
en
Publisher
Wageningen Academic
Rights
Attribution 4.0 International
Title
A genome-wide scan for signatures of selection in Hanwoo and Angus cattle using whole-genome sequence data
Type of document
Conference Publication
Entity Type
Publication

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