Xu, Ying; Phu, Jack; Aung, Htein Linn; Hesam-Shariati, Negin; Keay, Lisa; Tully, Phillip J; Booth, Andrew; Anderson, Craig S; Anstey, Kaarin J; Peters, Ruth

Author(s)

Xu, Ying

Phu, Jack

Aung, Htein Linn

Hesam-Shariati, Negin

Keay, Lisa

Tully, Phillip J

Booth, Andrew

Anderson, Craig S

Anstey, Kaarin J

Peters, Ruth

Publication Date

2023

Abstract

OBJECTIVE: We aim to quantify the co-existence of age-related macular degeneration (AMD), glaucoma, or diabetic retinopathy (DR) and cognitive impairment or dementia. METHOD: MEDLINE, EMBASE, PsycINFO and CINAHL were searched (to June 2020). Observational studies reporting incidence or prevalence of AMD, glaucoma, or DR in people with cognitive impairment or dementia, and of cognitive impairment or dementia among people with AMD, glaucoma, or DR were included. RESULTS: Fifty-six studies (57 reports) were included but marked by heterogeneities in the diagnostic criteria or definitions of the diseases, study design, and case mix. Few studies reported on the incidence. Evidence was sparse but consistent in individuals with mild cognitive impairment where 7.7% glaucoma prevalence was observed. Prevalence of AMD and DR among people with cognitive impairment ranged from 3.9% to 9.4% and from 11.4% to 70.1%, respectively. Prevalence of AMD and glaucoma among people with dementia ranged from 1.4 to 53% and from 0.2% to 25.9%, respectively. Prevalence of DR among people with dementia was 11%. Prevalence of cognitive impairment in people with AMD, glaucoma, and DR ranged from 8.4% to 52.4%, 12.3% to 90.2%, and 3.9% to 77.8%, respectively, and prevalence of dementia in people with AMD, glaucoma and DR ranged from 9.9% to 62.6%, 2.5% to 3.3% and was 12.5%, respectively. CONCLUSIONS: Frequency of comorbid eye disease and cognitive impairment or dementia varied considerably. While more population-based estimations of the co-existence are needed, interdisciplinary collaboration might be helpful in the management of these conditions to meet healthcare needs of an ageing population.

Citation

Eye, v.37, p. 3128-3136

ISSN

1476-5454

0950-222X

Pubmed ID

36922645

Link

https://hdl.handle.net/1959.11/55365

Publisher

Nature Publishing Group

Rights

Attribution 4.0 International

Title

Frequency of coexistent eye diseases and cognitive impairment or dementia: a systematic review and meta-analysis

Type of document

Journal Article

Entity Type

Publication

Name	Size	format	Description	Link
administrative/FrequencyOfCoexistentTully2023JournArticleEarlyOnline.pdf	1035.965 KB	application/pdf	Early online version	View document
openpublished/FrequencyTully2023JournalArticle.pdf	1024.921 KB	application/pdf	Published version	View document

Author(s)	Xu, Ying Phu, Jack Aung, Htein Linn Hesam-Shariati, Negin Keay, Lisa Tully, Phillip J Booth, Andrew Anderson, Craig S Anstey, Kaarin J Peters, Ruth
Publication Date	2023
Abstract	<p><b>OBJECTIVE:</b> We aim to quantify the co-existence of age-related macular degeneration (AMD), glaucoma, or diabetic retinopathy (DR) and cognitive impairment or dementia.</p> <p><b>METHOD:</b> MEDLINE, EMBASE, PsycINFO and CINAHL were searched (to June 2020). Observational studies reporting incidence or prevalence of AMD, glaucoma, or DR in people with cognitive impairment or dementia, and of cognitive impairment or dementia among people with AMD, glaucoma, or DR were included.</p> <p><b>RESULTS:</b> Fifty-six studies (57 reports) were included but marked by heterogeneities in the diagnostic criteria or definitions of the diseases, study design, and case mix. Few studies reported on the incidence. Evidence was sparse but consistent in individuals with mild cognitive impairment where 7.7% glaucoma prevalence was observed. Prevalence of AMD and DR among people with cognitive impairment ranged from 3.9% to 9.4% and from 11.4% to 70.1%, respectively. Prevalence of AMD and glaucoma among people with dementia ranged from 1.4 to 53% and from 0.2% to 25.9%, respectively. Prevalence of DR among people with dementia was 11%. Prevalence of cognitive impairment in people with AMD, glaucoma, and DR ranged from 8.4% to 52.4%, 12.3% to 90.2%, and 3.9% to 77.8%, respectively, and prevalence of dementia in people with AMD, glaucoma and DR ranged from 9.9% to 62.6%, 2.5% to 3.3% and was 12.5%, respectively.</p> <p><b>CONCLUSIONS:</b> Frequency of comorbid eye disease and cognitive impairment or dementia varied considerably. While more population-based estimations of the co-existence are needed, interdisciplinary collaboration might be helpful in the management of these conditions to meet healthcare needs of an ageing population.</p>
Citation	Eye, v.37, p. 3128-3136
ISSN	1476-5454 0950-222X
Pubmed ID	36922645
Link	https://hdl.handle.net/1959.11/55365
Publisher	Nature Publishing Group
Rights	Attribution 4.0 International
Title	Frequency of coexistent eye diseases and cognitive impairment or dementia: a systematic review and meta-analysis
Type of document	Journal Article
Entity Type	Publication

Frequency of coexistent eye diseases and cognitive impairment or dementia: a systematic review and meta-analysis

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