Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/53901
Title: Assessment of Potentially Inappropriate Prescribing for People With Type 2 Diabetes Mellitus Using IMPACT2DM, a New Explicit Tool
Contributor(s): Ayalew, Mohammed B  (author)orcid ; Dieberg, Gudrun  (author)orcid ; Quirk, Frances  (author); Spark, Marion J  (author)orcid 
Publication Date: 2024-06
Early Online Version: 2022-12-16
DOI: 10.1177/08971900221145219
Handle Link: https://hdl.handle.net/1959.11/53901
Abstract: 

Background: People with type 2 diabetes mellitus (T2DM) are at greater risk of potentially inappropriate prescribing (PIP) due to multiple comorbidities and polypharmacy. IMPACT2DM (Inappropriate Medication Prescribing Assessment Criteria for Type 2 Diabetes Mellitus) is a tool designed to identify PIP for adults with T2DM.

Objectives: To assess PIP for adults with T2DM in Ethiopia using the IMPACT2DM and to test the face validity and clinical validity of the tool.

Methods: A cross-sectional study was undertaken using data extracted retrospectively from the medical records of adults being managed for T2DM at Debretabore Hospital. PIP was assessed using IMPACT2DM. Some items/item components of IMPACT2DM were modified to increase the tool’s applicability for the outpatient setting, to clarify content or to use the terms most common in this particular setting. Multivariant logistic regression analyses were conducted to identify factors associated with PIP.

Results: More than 90% of medical records had at least 1 PIP. Prescribing omission (80.9%) was the most commonly identified type of PIP. Adults with prescribing omissions are more likely to be ≥40 years old or to be prescribed with <5 medications. Adults with dosing problems were more likely ≥50 years old, or have had a fasting blood sugar (FBS) level out of the target range (80-130 mg/dL).

Conclusions: IMPACT2DM is a clinically valid PIP identification tool for application in an Ethiopian outpatient setting. Health professionals should be alert to check for potential prescribing omissions for adults ≥40 years old and dosing problems for adults with an FBS level out of the target range or >50 years.

Publication Type: Journal Article
Source of Publication: Journal of Pharmacy Practice, 37(3), p. 546-556
Publisher: Sage Publications, Inc
Place of Publication: United States of America
ISSN: 1531-1937
0897-1900
Fields of Research (FoR) 2020: 321403 Clinical pharmacy and pharmacy practice
Socio-Economic Objective (SEO) 2020: 200303 Health surveillance
200308 Outpatient care
200310 Primary care
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
Appears in Collections:Journal Article
School of Rural Medicine
School of Science and Technology

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