Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/53118
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dc.contributor.authorBrain, Jacoben
dc.contributor.authorTully, Phillip Jen
dc.contributor.authorTurnbull, Deborahen
dc.contributor.authorTang, Eugeneen
dc.contributor.authorGreene, Leanneen
dc.contributor.authorBeach, Sarahen
dc.contributor.authorSiervo, Marioen
dc.contributor.authorStephan, Blossom C Men
dc.date.accessioned2022-08-04T22:57:35Z-
dc.date.available2022-08-04T22:57:35Z-
dc.date.issued2022-07-21-
dc.identifier.citationPLoS One, 17(7), p. 1-9en
dc.identifier.issn1932-6203en
dc.identifier.urihttps://hdl.handle.net/1959.11/53118-
dc.description.abstract<b>Background</b><br/> Dementia is a major public health priority. Although there is abundant evidence of an associ-ation between dementia and poor cardiovascular health, findings have been inconsistent and uncertain in identifying which factors increase dementia risk in those with cardiovascular disease. Indeed, multiple variables including sociodemographic, economic, health, lifestyle and education may indicate who is at higher vs. lower dementia risk and could be used in prediction modelling. Therefore, the aim of this review is to synthesise evidence on the key risk factors for dementia in those with a history of cardiovascular disease.<br/> <br/><b>Methods</b><br/> This is an overview of reviews protocol, registered on PROSPERO (CRD42021265363). Four electronic databases including MEDLINE, EMBASE, PsycINFO, and the Cochrane Database of Systematic Reviews will be searched. Studies will be included if they are systematic reviews and/or meta-analyses that have investigated the risk of incident dementia (all-cause and subtypes including Alzheimer's disease and vascular dementia) in people with a history of coronary heart disease, heart failure, atrial fibrillation, hypertension, hyperli-pidaemia, and vascular stiffness. Study selection will be completed by two independent researchers according to the eligibility criteria, and conflicts resolved by a third reviewer. References will be exported into Covidence for title and abstract sifting, full-text review, and data extraction. Methodological quality will be assessed using the AMSTAR-2 criteria and confidence of evidence will be assessed using the GRADE classification. This overview of reviews will follow PRISMA guidelines. If there is sufficient homogeneity in the data, the results will be pooled, and a meta-analysis conducted to determine the strength ofassociation between each risk factor and incident all-cause dementia and its subtypes for each cardiovascular diagnoses separately.<br/><br/><b>Discussion</b><br/> We will create a comprehensive summary of the key risk factors linking cardiovascular dis-eases to risk of incident dementia. This knowledge is essential for informing risk predictive model development as well as the development of risk reduction and prevention strategies.en
dc.languageenen
dc.publisherPublic Library of Scienceen
dc.relation.ispartofPLoS Oneen
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.titleRisk factors for dementia in the context of cardiovascular disease: A protocol of an overview of reviewsen
dc.typeJournal Articleen
dc.identifier.doi10.1371/journal.pone.0271611en
dc.identifier.pmid35862400en
dcterms.accessRightsUNE Greenen
local.contributor.firstnameJacoben
local.contributor.firstnamePhillip Jen
local.contributor.firstnameDeborahen
local.contributor.firstnameEugeneen
local.contributor.firstnameLeanneen
local.contributor.firstnameSarahen
local.contributor.firstnameMarioen
local.contributor.firstnameBlossom C Men
local.profile.schoolSchool of Psychologyen
local.profile.emailptully2@une.edu.auen
local.output.categoryC1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.publisher.placeUnited States of Americaen
local.identifier.runningnumbere0271611en
local.format.startpage1en
local.format.endpage9en
local.identifier.scopusid85134817781en
local.peerreviewedYesen
local.identifier.volume17en
local.identifier.issue7en
local.title.subtitleA protocol of an overview of reviewsen
local.access.fulltextYesen
local.contributor.lastnameBrainen
local.contributor.lastnameTullyen
local.contributor.lastnameTurnbullen
local.contributor.lastnameTangen
local.contributor.lastnameGreeneen
local.contributor.lastnameBeachen
local.contributor.lastnameSiervoen
local.contributor.lastnameStephanen
dc.identifier.staffune-id:ptully2en
local.profile.orcid0000-0003-2807-1313en
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
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local.identifier.unepublicationidune:1959.11/53118en
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
local.title.maintitleRisk factors for dementia in the context of cardiovascular diseaseen
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.search.authorBrain, Jacoben
local.search.authorTully, Phillip Jen
local.search.authorTurnbull, Deborahen
local.search.authorTang, Eugeneen
local.search.authorGreene, Leanneen
local.search.authorBeach, Sarahen
local.search.authorSiervo, Marioen
local.search.authorStephan, Blossom C Men
local.open.fileurlhttps://rune.une.edu.au/web/retrieve/b3f01df1-3a8d-4552-9aae-f663b95479a4en
local.uneassociationYesen
local.atsiresearchNoen
local.sensitive.culturalNoen
local.year.published2022-
local.fileurl.openhttps://rune.une.edu.au/web/retrieve/b3f01df1-3a8d-4552-9aae-f663b95479a4en
local.fileurl.openpublishedhttps://rune.une.edu.au/web/retrieve/b3f01df1-3a8d-4552-9aae-f663b95479a4en
local.subject.for2020520106 Psychology of ageingen
local.subject.seo2020200201 Determinants of healthen
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School of Psychology
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