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QTL mapping for feed conversion efficiency on porcine chromosome 10 in an Australian commercial population |
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Editor(s): Alex Safari, Bill Pattie, Barrie Restall |
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Association for the Advancement of Animal Breeding and Genetics (AAABG) |
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A genetic linkage map of 23 markers on porcine chromosome 10 was constructed with a resource pedigree based on an Australian commercial pig population. Six new markers (UMNP885, UMNP1049, UMNP875, UMNP925, UMNP876 and UMNP519) were linkage mapped to porcine chromosome 10 for the first time. Phenotypes were available for juvenile IGF-I along with feed intake, average daily gain and feed conversion ratio (FCR) recorded over a 6 week performance test period; associations between QTL and residuals for these traits were investigated. A significant QTL for FCR was found between marker UMNP875 and UMNP925 by single family and across family analysis with maximum likelihood using composite interval mapping, confirmed by linkage disequilibrum and linkage analysis (LDLA). In single family analyses, a significant QTL for average daily gain was found in sire family 896TS and an IGF-I QTL was found in sire family 52103. The study provided strong justification for further fine mapping and positional cloning of causative genes for FCR on chromosome 10 for marker assisted selection in pig breeding. |
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Proceedings of the Association for the Advancement of Animal Breeding and Genetics, v.18, p. 183-186 |
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