Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/5221
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dc.contributor.authorKhalil, Zen
dc.contributor.authorKhodr, Ben
dc.contributor.authorHoward, Jonathonen
dc.contributor.authorWatson, Kennethen
local.source.editorEditor(s): D Galarisen
dc.date.accessioned2010-03-19T08:46:00Z
dc.date.issued2003en
dc.identifier.citationFree Radicals and Oxidative Stress: Chemistry, Biochemistry and Pathophysiological Implications - Proceedings of the Meeting of the Society for Free Radicals Research, European Section, p. 133-138en
dc.identifier.isbn8875870020en
dc.identifier.urihttps://hdl.handle.net/1959.11/5221en
dc.description.abstractPrevious studies from our laboratory demonstrated an age-related functional decline in wound repair. Emerging evidence from our group and others favours the involvement of oxidative damage in the pathogenesis of age-related deficits. The aim of this study was to investigate the impact of vitamin E therapy on modulating oxidative stress markers and repair of full-thickness wounds in aged animals. Twenty four-month-old Sprague-Dawley rats were treated with vitamin E for short-term (40mg/kg, i.p. every other day for 2 weeks) or long-term (for 12 months in advance, 10g/kg, incorporated in food). The results indicate that both treatments were effective in reducing oxidative damage and in accelerating wound closure in aged rats. However, an initial increase in wound size was observed in both treated groups. This side effect of a single antioxidant therapy could reflect the importance of oxidants in the early stages of the repair process.en
dc.languageenen
dc.publisherMedimonden
dc.relation.ispartofFree Radicals and Oxidative Stress: Chemistry, Biochemistry and Pathophysiological Implications - Proceedings of the Meeting of the Society for Free Radicals Research, European Sectionen
dc.titleVitamin E Reduces Oxidative Stress Markers and Modulates Wound Repair in Aged Animalsen
dc.typeConference Publicationen
dc.relation.conferenceMeeting of the Society for Free Radicals Research, European Section, Ioannina, Greece, 26th June - 29th June, 2003en
dc.subject.keywordsClinical Sciencesen
local.contributor.firstnameZen
local.contributor.firstnameBen
local.contributor.firstnameJonathonen
local.contributor.firstnameKennethen
local.subject.for2008110399 Clinical Sciences not elsewhere classifieden
local.subject.seo2008920409 Injury Controlen
local.profile.schoolSchool of Science and Technologyen
local.profile.schoolAdministrationen
local.profile.emailkwatson2@une.edu.auen
local.output.categoryB1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.identifier.epublicationsrecordpes:693en
local.publisher.placeBologna, Italyen
local.format.startpage133en
local.format.endpage138en
local.peerreviewedYesen
local.contributor.lastnameKhalilen
local.contributor.lastnameKhodren
local.contributor.lastnameHowarden
local.contributor.lastnameWatsonen
dc.identifier.staffune-id:kwatson2en
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:5339en
dc.identifier.academiclevelAcademicen
local.title.maintitleVitamin E Reduces Oxidative Stress Markers and Modulates Wound Repair in Aged Animalsen
local.output.categorydescriptionB1 Chapter in a Scholarly Booken
local.relation.urlhttp://www.medimond.com/proceedings/moreinfo/20030627.htmen
local.description.statisticsepubsVisitors: 85<br />Views: 96<br />Downloads: 0en
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