Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/51363
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dc.contributor.authorKebeta, M Men
dc.contributor.authorHine, B Cen
dc.contributor.authorWalkden-Brown, S Wen
dc.contributor.authorKahn, L Pen
dc.contributor.authorDoyle, E Ken
dc.date.accessioned2022-03-22T04:08:33Z-
dc.date.available2022-03-22T04:08:33Z-
dc.date.issued2020-07-
dc.identifier.citationVeterinary Parasitology, v.283, p. 1-6en
dc.identifier.issn1873-2550en
dc.identifier.issn0304-4017en
dc.identifier.urihttps://hdl.handle.net/1959.11/51363-
dc.description.abstract<p>The Barbervax<sup>®</sup> vaccine, directed against <i>Haemonchus contortus</i>, has been commercially available in Australia since 2014. However, to date the optimal timing for booster vaccination of lambing ewes has not been identified. Therefore the aim of this experiment was to compare the efficacy of Barbervax<sup>®</sup> when administered to ewes one week prior to the commencement of lambing versus at lamb marking 7 weeks later. A total of 400 single bearing Merino ewes, run on a commercial sheep property in the New England region of New South Wales, previously primed with Barbervax<sup>®</sup> were enrolled in the project. The experiment incorporated a cross-over design with two treatments imposed pre-lambing; Barbervax<sup>®</sup> booster vaccination with anthelmintic (n = 200) or anthelmintic alone (n = 200). At lamb marking, there were four treatment groups (n = 100) and anthelmintic was administered to all treatment groups. The four treatment combinations were Barbervax<sup>®</sup> booster vaccination at pre-lambing and lamb marking (V-V), booster vaccination only at pre-lambing (V-A), booster vaccination only at lamb marking (A-V) or anthelmintic only at both at pre-lambing and lamb marking (A-A). Pre-lambing Barbervax<sup>®</sup> booster vaccination of ewes induced an antibody response and, when used in conjunction with anthelmintic, significantly reduced worm egg counts (WEC) assessed at 7 weeks (lamb marking) and 13 weeks later, relative to treatment with anthelmintic alone. Booster vaccination plus anthelmintic treatment at lamb marking was not effective at reducing WEC compared to anthelmintic treatment alone. Body weight and packed cell volume did not differ between the treatment groups throughout the trial. In conclusion Barbervax<sup>®</sup> booster vaccination at pre-lambing provides additional protection for reproducing ewes given an effective short acting anthelmintic at this time.</p>en
dc.languageenen
dc.publisherElsevier BVen
dc.relation.ispartofVeterinary Parasitologyen
dc.titleEvaluation of Barbervax(R) vaccination for lambing Merino ewesen
dc.typeJournal Articleen
dc.identifier.doi10.1016/j.vetpar.2020.109187en
dc.identifier.pmid32702608en
local.contributor.firstnameM Men
local.contributor.firstnameB Cen
local.contributor.firstnameS Wen
local.contributor.firstnameL Pen
local.contributor.firstnameE Ken
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.emailmkebeta@myune.edu.auen
local.profile.emailswalkden@une.edu.auen
local.profile.emaillkahn3@une.edu.auen
local.profile.emailedoyle3@une.edu.auen
local.output.categoryC1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.publisher.placeNetherlandsen
local.identifier.runningnumber109187en
local.format.startpage1en
local.format.endpage6en
local.identifier.scopusid85088087830en
local.peerreviewedYesen
local.identifier.volume283en
local.contributor.lastnameKebetaen
local.contributor.lastnameHineen
local.contributor.lastnameWalkden-Brownen
local.contributor.lastnameKahnen
local.contributor.lastnameDoyleen
dc.identifier.staffune-id:mkebetaen
dc.identifier.staffune-id:swalkdenen
dc.identifier.staffune-id:lkahn3en
dc.identifier.staffune-id:edoyle3en
local.profile.orcid0000-0002-0638-5533en
local.profile.orcid0000-0002-3679-4530en
local.profile.orcid0000-0002-5255-2187en
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.profile.roleauthoren
local.identifier.unepublicationidune:1959.11/51363en
local.date.onlineversion2020-07-13-
dc.identifier.academiclevelStudenten
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
dc.identifier.academiclevelAcademicen
local.title.maintitleEvaluation of Barbervax(R) vaccination for lambing Merino ewesen
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.search.authorKebeta, M Men
local.search.authorHine, B Cen
local.search.authorWalkden-Brown, S Wen
local.search.authorKahn, L Pen
local.search.authorDoyle, E Ken
local.uneassociationYesen
local.atsiresearchNoen
local.sensitive.culturalNoen
local.identifier.wosid000564698900006en
local.year.available2020en
local.year.published2020en
local.fileurl.closedpublishedhttps://rune.une.edu.au/web/retrieve/8365cdbf-67df-4847-ac3e-589ec6eb734cen
local.subject.for2020300304 Animal protection (incl. pests and pathogens)en
local.subject.for2020300909 Veterinary parasitologyen
local.subject.seo2020100413 Sheep for woolen
local.subject.seo2020100412 Sheep for meaten
Appears in Collections:Journal Article
School of Environmental and Rural Science
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