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https://hdl.handle.net/1959.11/5061
Title: | Kava Anxiety Depression Spectrum Study (KADSS): A mixed methods RCT using an aqueous extract of 'Piper methysticum' | Contributor(s): | Sarris, J (author); Kavanagh, DJ (author); Adams, J (author); Bone, Kerry (author); Byrne, G (author) | Publication Date: | 2009 | DOI: | 10.1016/j.ctim.2009.01.001 | Handle Link: | https://hdl.handle.net/1959.11/5061 | Abstract: | Objectives To report on the design, significance and potential impacts of the first documented human clinical trial assessing the anxiolytic and thymoleptic efficacy of an aqueous mono-extract of Piper methysticum (kava). The significance of the qualitative element of our clinical trial is also explored. The Kava Anxiety Depression Spectrum Study (KADSS) is a 3-week placebo-controlled, double-blind, cross-over trial involving 60 adult participants (18–65) with elevated stable anxiety and varying levels of depressive symptoms. Aims The aims of KADSS are: (1) to determine whether an aqueous standardised extract of kava is effective for the treatment of anxiety; (2) to assess the effects of kava on differing levels of depression; and (3) to explore participants’ experience of taking kava via qualitative research. The study also provides preliminary assessment of the safety of an aqueous extract of kava in humans. Conclusion If results reveal that the aqueous kava preparation exerts significant anxiolytic effects and appears safe, potentially beneficial impacts may occur. Data supporting a safe and effective kava extract may encourage a re-introduction of kava to Europe, UK and Canada. This may provide a major socioeconomic benefit to Pacific Island nations, and to sufferers of anxiety disorders. | Publication Type: | Journal Article | Source of Publication: | Complementary Therapies in Medicine, 17(3), p. 176-178 | Publisher: | Churchill Livingstone | Place of Publication: | United Kingdom | ISSN: | 1873-6963 0965-2299 |
Fields of Research (FoR) 2008: | 110499 Complementary and Alternative Medicine not elsewhere classified | Socio-Economic Objective (SEO) 2008: | 929999 Health not elsewhere classified | Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal |
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Appears in Collections: | Journal Article |
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