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https://hdl.handle.net/1959.11/4899
Title: | A major SNP resource for dissection of phenotypic and genetic variation in Pacific white shrimp ('Litopenaeus vannamei') | Contributor(s): | Ciobanu, Daniel C (author); Bastiaansen, John W M (author); Plastow, G S P (author); van der Steen, H A M (author); Mileham, Alan (author); Magrin, J (author); Rocha, Joao (author); Jiang, D (author); Yu, Nan (author); Geiger, B (author); Deeb, Nader (author); Rocha, D (author); Kinghorn, Brian (author) | Publication Date: | 2010 | DOI: | 10.1111/j.1365-2052.2009.01961.x | Handle Link: | https://hdl.handle.net/1959.11/4899 | Abstract: | Bioinformatics and re-sequencing approaches were used for the discovery of sequence polymorphisms in 'Litopenaeus vannamei'. A total of 1221 putative single nucleotide polymorphisms (SNPs) were identified in a pool of individuals from various commercial populations. A set of 211 SNPs were selected for further molecular validation and 88% showed variation in 637 samples representing three commercial breeding lines. An association analysis was performed between these markers and several traits of economic importance for shrimp producers including resistance to three major viral diseases. A small number of SNPs showed associations with test weekly gain, grow-out survival and resistance to Taura Syndrome Virus. Very low levels of linkage disequilibrium were revealed between most SNP pairs, with only 11% of SNPs showing an r²-value above 0.10 with at least one other SNP. Comparison of allele frequencies showed small changes over three generations of the breeding programme in one of the commercial breeding populations. This unique SNP resource has the potential to catalyse future studies of genetic dissection of complex traits, tracing relationships in breeding programmes, and monitoring genetic diversity in commercial and wild populations of 'L. vannamei'. | Publication Type: | Journal Article | Source of Publication: | Animal Genetics, 41(1), p. 39-47 | Publisher: | Wiley-Blackwell Publishing Ltd | Place of Publication: | United Kingdom | ISSN: | 1365-2052 0268-9146 |
Fields of Research (FoR) 2008: | 070405 Fish Physiology and Genetics 070401 Aquaculture |
Socio-Economic Objective (SEO) 2008: | 830105 Aquaculture Prawns | Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal |
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Appears in Collections: | Journal Article |
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