Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/4878
Title: A Recursive Algorithm For Long Range Phasing Of SNP Genotype
Contributor(s): Kinghorn, Brian  (author); Hickey, John (author); Van Der Werf, Julius H  (author)orcid 
Publication Date: 2009
Handle Link: https://hdl.handle.net/1959.11/4878
Abstract: High density genotyping of individuals does not by itself yield information on phase: linkage of alleles between loci in the contributing gametes. This additional information is important, because it helps to determine which segments of chromosome are identical by descent across the population, and thereby improve inference about segregation of quantitative trait loci (QTL). This paper presents a recursive algorithm to give efficient implementation of long range phasing, a recently-published strategy that infers IBD between distant relatives from long strings of SNP genotypes that show no opposing homozygotes (i.e. no evidence of lack of IBS). These relatives can be both distant and unknown to the analysis. Successful implementation of this strategy gives opportunity to use haplotype and/or combined linkage-linkage disequilibrium analysis for QTL mapping or genomic selection.
Publication Type: Conference Publication
Conference Name: 18th Conference AAABG: Association for the Advancement of Animal Breeding and Genetics: Matching Genetics and the Environment a New Look at and Old Topic, Barossa Valley, Australia, 27th September - 2nd October, 2009
Conference Details: 18th Conference AAABG: Association for the Advancement of Animal Breeding and Genetics: Matching Genetics and the Environment a New Look at and Old Topic, Barossa Valley, Australia, 27th September - 2nd October, 2009
Source of Publication: Proceedings of the 18th Conference AAABG: Association for the Advancement of Animal Breeding and Genetics: Matching Genetics and the Environment a New Look at and Old Topic, v.18, p. 76-79
Publisher: AAABG: Association for the Advancement of Animal Breeding and Genetics
Place of Publication: Adelaide, Australia
ISSN: 1328-3227
Field of Research (FOR): 060412 Quantitative Genetics (incl Disease and Trait Mapping Genetics)
070201 Animal Breeding
Peer Reviewed: Yes
HERDC Category Description: E1 Refereed Scholarly Conference Publication
Other Links: http://www.aaabg.org/proceedings18/files/kinghorn076.pdf
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