Insulin-like Growth Factor-I Measured (IGF-I) in Juvenile Pigs is Genetically Correlated with Economically Important Performance Traits

Bunter, K L; Hermesch, S; Luxford, B G; Graser, H -U; Crump, R E

Author(s)

Bunter, K L

Hermesch, S

Luxford, B G

Graser, H -U

Crump, R E

Publication Date

2005-09

Abstract

Insulin-like growth factor-I (IGF-I) is a naturally occurring polypeptide produced in the liver, muscle and fat tissues. It is known to be associated with growth and development during the post-natal growth period. Evidence for strong genetic correlations between juvenile IGF-I and performance traits would suggest this physiological measure would be useful as an early selection criterion. This paper reports estimates of genetic parameters from 9 trials where IGF-I was measured in juvenile pigs. All trials involved populations undergoing active selection for improved performance (e.g. efficient lean meat growth). Juvenile IGF-I was moderately heritable (average h2: 0.31) and influenced by common litter effects (average c2: 0.15). Genetic correlations (rg) between juvenile IGF-I and backfat (BF), feed intake (FI) or feed conversion ratio (FCR) traits were generally large and positive: rg averaged 0.57, 0.41 and 0.65, respectively. Phenotypic correlations (rp) between juvenile IGF-I and BF, FI or FCR were much lower (rp averaged 0.21, 0.09, and 0.15, respectively) as residual correlations between IGF-I and these performance traits were low, consistent with being measured at very different times. Correlations (genetic or phenotypic) between juvenile IGF-I and growth traits (e.g. lifetime daily gain or test daily gain) were relatively low, with average values within ± 0.09 of zero. Results from the trials reported here, and several physiological studies, indicate that information on juvenile IGF-I concentration can be used as an early physiological indicator of performance traits traditionally measured later in life. There is a clear role for juvenile IGF-I to facilitate pre-selection and more accurate selection of livestock for hard to measure traits, such as FCR, in pig breeding programmes.

Citation

Proceedings of the Association for the Advancement of Animal Breeding and Genetics, v.16, p. 90-90

ISBN

0643092331

064309234X

ISSN

1328-3227

Link

https://hdl.handle.net/1959.11/4555

Language

en

Title

Insulin-like Growth Factor-I Measured (IGF-I) in Juvenile Pigs is Genetically Correlated with Economically Important Performance Traits

Type of document

Conference Publication

Entity Type

Publication

Author(s)	Bunter, K L Hermesch, S Luxford, B G Graser, H -U Crump, R E
Publication Date	2005-09
Abstract	Insulin-like growth factor-I (IGF-I) is a naturally occurring polypeptide produced in the liver, muscle and fat tissues. It is known to be associated with growth and development during the post-natal growth period. Evidence for strong genetic correlations between juvenile IGF-I and performance traits would suggest this physiological measure would be useful as an early selection criterion. This paper reports estimates of genetic parameters from 9 trials where IGF-I was measured in juvenile pigs. All trials involved populations undergoing active selection for improved performance (e.g. efficient lean meat growth). Juvenile IGF-I was moderately heritable (average h2: 0.31) and influenced by common litter effects (average c2: 0.15). Genetic correlations (rg) between juvenile IGF-I and backfat (BF), feed intake (FI) or feed conversion ratio (FCR) traits were generally large and positive: rg averaged 0.57, 0.41 and 0.65, respectively. Phenotypic correlations (rp) between juvenile IGF-I and BF, FI or FCR were much lower (rp averaged 0.21, 0.09, and 0.15, respectively) as residual correlations between IGF-I and these performance traits were low, consistent with being measured at very different times. Correlations (genetic or phenotypic) between juvenile IGF-I and growth traits (e.g. lifetime daily gain or test daily gain) were relatively low, with average values within ± 0.09 of zero. Results from the trials reported here, and several physiological studies, indicate that information on juvenile IGF-I concentration can be used as an early physiological indicator of performance traits traditionally measured later in life. There is a clear role for juvenile IGF-I to facilitate pre-selection and more accurate selection of livestock for hard to measure traits, such as FCR, in pig breeding programmes.
Citation	Proceedings of the Association for the Advancement of Animal Breeding and Genetics, v.16, p. 90-90
ISBN	0643092331 064309234X
ISSN	1328-3227
Link	https://hdl.handle.net/1959.11/4555
Language	en
Title	Insulin-like Growth Factor-I Measured (IGF-I) in Juvenile Pigs is Genetically Correlated with Economically Important Performance Traits
Type of document	Conference Publication
Entity Type	Publication

Insulin-like Growth Factor-I Measured (IGF-I) in Juvenile Pigs is Genetically Correlated with Economically Important Performance Traits

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