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|Title:||Insulin-like Growth Factor-I Measured (IGF-I) in Juvenile Pigs is Genetically Correlated with Economically Important Performance Traits||Contributor(s):||Bunter, Kim Louise (author); Hermesch, Susanne (author) ; Luxford, BG (author); Graser, Hans Ulrich (author); Crump, Ronald Edward (author)||Publication Date:||2005||Handle Link:||https://hdl.handle.net/1959.11/4555||Abstract:||Insulin-like growth factor-I (IGF-I) is a naturally occurring polypeptide produced in the liver, muscle and fat tissues. It is known to be associated with growth and development during the post-natal growth period. Evidence for strong genetic correlations between juvenile IGF-I and performance traits would suggest this physiological measure would be useful as an early selection criterion. This paper reports estimates of genetic parameters from 9 trials where IGF-I was measured in juvenile pigs. All trials involved populations undergoing active selection for improved performance (e.g. efficient lean meat growth). Juvenile IGF-I was moderately heritable (average h2: 0.31) and influenced by common litter effects (average c2: 0.15). Genetic correlations (rg) between juvenile IGF-I and backfat (BF), feed intake (FI) or feed conversion ratio (FCR) traits were generally large and positive: rg averaged 0.57, 0.41 and 0.65, respectively. Phenotypic correlations (rp) between juvenile IGF-I and BF, FI or FCR were much lower (rp averaged 0.21, 0.09, and 0.15, respectively) as residual correlations between IGF-I and these performance traits were low, consistent with being measured at very different times. Correlations (genetic or phenotypic) between juvenile IGF-I and growth traits (e.g. lifetime daily gain or test daily gain) were relatively low, with average values within ± 0.09 of zero. Results from the trials reported here, and several physiological studies, indicate that information on juvenile IGF-I concentration can be used as an early physiological indicator of performance traits traditionally measured later in life. There is a clear role for juvenile IGF-I to facilitate pre-selection and more accurate selection of livestock for hard to measure traits, such as FCR, in pig breeding programmes.||Publication Type:||Conference Publication||Conference Name:||16th Conference of the Association for the Advancement of Animal Breeding and Genetics, Noosa Lakes, Australia, 25th - 28th September, 2005||Conference Details:||16th Conference of the Association for the Advancement of Animal Breeding and Genetics, Noosa Lakes, Australia, 25th - 28th September, 2005||Source of Publication:||Application of new genetic technologies to animal breeding: Proceedings of the 16th Conference of the Association for the Advancement of Animal Breeding and Genetics, p. 90-90||Publisher:||CSIRO Publishing||Place of Publication:||Collingwood, Australia||ISSN:||1328-3227||Field of Research (FOR):||070201 Animal Breeding||Socio-Economic Outcome Codes:||830308 Pigs||HERDC Category Description:||E3 Extract of Scholarly Conference Publication||Other Links:||http://trove.nla.gov.au/work/13321110
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|Appears in Collections:||Animal Genetics and Breeding Unit (AGBU)|
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