Please use this identifier to cite or link to this item:
https://hdl.handle.net/1959.11/4517
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, S H | en |
dc.contributor.author | Van Der Werf, Julius Herman | en |
local.source.editor | Editor(s): Abigail Henderson | en |
dc.date.accessioned | 2010-02-05T16:21:00Z | - |
dc.date.issued | 2003 | - |
dc.identifier.citation | Proceedings of the Association for the Advancement of Animal Breeding and Genetics, v.15, p. 9-13 | en |
dc.identifier.isbn | 0958629927 | en |
dc.identifier.issn | 1328-3227 | en |
dc.identifier.uri | https://hdl.handle.net/1959.11/4517 | - |
dc.description.abstract | This study showed that common half sib designs can obtain sufficient linkage disequilibrium (LD) information for fine-mapping of quantitative trait loci (QTL). A design of two large half sib families was applied to a hypothetical population with an effective size (Ne) of 1000 simulated for 6000 generations. 70 ~ 75% of replicates could position QTL within 0.75 cM when mutation age was more than 200 generations in mapping using multi-allelic markers. When Ne was linearly decreasing (1000 to 100) in the last 50 generations, the accuracy of QTL mapping was decreased to only 50 to 70% of replicates that could position QTL within 0.75 cM. Provided that QTL allele segregates in the dam population, it is advantageous to use the same half sib design in linkage mapping and fine-mapping making gene mapping cost effective in livestock populations. | en |
dc.language | en | en |
dc.publisher | Association for the Advancement of Animal Breeding and Genetics (AAABG) | en |
dc.relation.ispartof | Proceedings of the Association for the Advancement of Animal Breeding and Genetics | en |
dc.title | Efficient designs for fine-mapping of quantitative trait loci using linkage disequilibrium and linkage | en |
dc.type | Conference Publication | en |
dc.relation.conference | AAABG 2003: 15th Conference of the Association for the Advancement of Animal Breeding and Genetics | en |
dc.subject.keywords | Quantitative Genetics (incl Disease and Trait Mapping Genetics) | en |
local.contributor.firstname | S H | en |
local.contributor.firstname | Julius Herman | en |
local.subject.for2008 | 060412 Quantitative Genetics (incl Disease and Trait Mapping Genetics) | en |
local.subject.seo2008 | 839999 Animal Production and Animal Primary Products not elsewhere classified | en |
local.profile.school | School of Environmental and Rural Science | en |
local.profile.email | jvanderw@une.edu.au | en |
local.output.category | E1 | en |
local.record.place | au | en |
local.record.institution | University of New England | en |
local.identifier.epublicationsrecord | pes:936 | en |
local.date.conference | 7th July - 11th July, 2003 | en |
local.conference.place | Melbourne, Australia | en |
local.publisher.place | Armidale, Australia | en |
local.format.startpage | 9 | en |
local.format.endpage | 13 | en |
local.peerreviewed | Yes | en |
local.identifier.volume | 15 | en |
local.contributor.lastname | Lee | en |
local.contributor.lastname | Van Der Werf | en |
dc.identifier.staff | une-id:jvanderw | en |
local.profile.orcid | 0000-0003-2512-1696 | en |
local.profile.role | author | en |
local.profile.role | author | en |
local.identifier.unepublicationid | une:4624 | en |
dc.identifier.academiclevel | Academic | en |
local.title.maintitle | Efficient designs for fine-mapping of quantitative trait loci using linkage disequilibrium and linkage | en |
local.output.categorydescription | E1 Refereed Scholarly Conference Publication | en |
local.relation.url | http://trove.nla.gov.au/work/10355225 | en |
local.relation.url | http://www.aaabg.org/livestocklibrary/2003/9-13.pdf | en |
local.conference.details | AAABG 2003: 15th Conference of the Association for the Advancement of Animal Breeding and Genetics, Melbourne, Australia, 7-11 July, 2003 | en |
local.search.author | Lee, S H | en |
local.search.author | Van Der Werf, Julius Herman | en |
local.uneassociation | Unknown | en |
local.year.published | 2003 | en |
local.date.start | 2003-07-07 | - |
local.date.end | 2003-07-11 | - |
Appears in Collections: | Conference Publication |
Files in This Item:
File | Description | Size | Format |
---|
Page view(s)
1,202
checked on Mar 24, 2024
Download(s)
2
checked on Mar 24, 2024
Items in Research UNE are protected by copyright, with all rights reserved, unless otherwise indicated.