Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/4500
Title: A genome scan for quantitative trait loci for resistance to the gastrointestinal parasite 'Haemonchus contortus' in sheep
Contributor(s): Marshall, Karen Lisa (author); Van Der Werf, Julius Herman  (author)orcid ; Maddox, J F (author); Graser, Hans Ulrich  (author); Zhang, Yuandan  (author); Walkden-Brown, Steve William  (author)orcid ; Kahn, Lewis  (author)orcid 
Publication Date: 2005
Handle Link: https://hdl.handle.net/1959.11/4500
Abstract: This paper presents some results from a genome scan for QTL affecting resistance to the gastrointestinal nematode Haemonchus contortus. The mapping flock comprised 571 sheep from four half-sib families, sired by individuals from the Golden Ram flock. The traits analysed were faecal egg counts after two artificial challenges at 6 and 13 months of age, termed FEC12 and FEC34 respectively. The correlation between these traits was low at 0.21. Animals were selectively genotyped for a total of 223 markers, and interval mapping performed on a within and across-family basis. For the within-family analysis 11 QTL (as chromosomal / family combinations) were significant at the 1% chromosome-wide (CW) level, with a further 18 significant at the 5% CW level. The allelic substitution effect (α) ranged from 0.19 to 0.50 phenotypic standard deviation units (σP). QTL significant at the 1%CW level were located on 9 different chromosomes, with only one of these regions significant for both FEC12 and FEC34. For the across-family analysis two chromosomal regions were significant at the 5%CW level, one each for FEC12 and FEC34.
Publication Type: Conference Publication
Conference Name: 16th Conference of the Association for the Advancement of Animal Breeding and Genetics, Noosa Lakes, Australia , 25th September - 28th September, 2005
Conference Details: 16th Conference of the Association for the Advancement of Animal Breeding and Genetics, Noosa Lakes, Australia , 25th September - 28th September, 2005
Source of Publication: Application of new genetic technologies to animal breeding: Proceedings of the 16th Conference of the Association for the Advancement of Animal Breeding and Genetics, p. 115-118
Publisher: CSIRO Publishing
Place of Publication: Collingwood, Australia
ISSN: 1328-3227
Field of Research (FOR): 070201 Animal Breeding
Socio-Economic Outcome Codes: 830311 Sheep - Wool
Peer Reviewed: Yes
HERDC Category Description: E1 Refereed Scholarly Conference Publication
Other Links: http://www.aaabg.org/livestocklibrary/2005/115marshall.pdf
http://trove.nla.gov.au/work/13321110?selectedversion=NBD28049210
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Appears in Collections:Animal Genetics and Breeding Unit (AGBU)
Conference Publication

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