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|Title:||A genome scan for quantitative trait loci for resistance to the gastrointestinal parasite 'Haemonchus contortus' in sheep||Contributor(s):||Marshall, Karen Lisa (author); Van Der Werf, Julius Herman (author) ; Maddox, J F (author); Graser, Hans Ulrich (author); Zhang, Yuandan (author); Walkden-Brown, Steve William (author) ; Kahn, Lewis (author)||Publication Date:||2005||Handle Link:||https://hdl.handle.net/1959.11/4500||Abstract:||This paper presents some results from a genome scan for QTL affecting resistance to the gastrointestinal nematode Haemonchus contortus. The mapping flock comprised 571 sheep from four half-sib families, sired by individuals from the Golden Ram flock. The traits analysed were faecal egg counts after two artificial challenges at 6 and 13 months of age, termed FEC12 and FEC34 respectively. The correlation between these traits was low at 0.21. Animals were selectively genotyped for a total of 223 markers, and interval mapping performed on a within and across-family basis. For the within-family analysis 11 QTL (as chromosomal / family combinations) were significant at the 1% chromosome-wide (CW) level, with a further 18 significant at the 5% CW level. The allelic substitution effect (α) ranged from 0.19 to 0.50 phenotypic standard deviation units (σP). QTL significant at the 1%CW level were located on 9 different chromosomes, with only one of these regions significant for both FEC12 and FEC34. For the across-family analysis two chromosomal regions were significant at the 5%CW level, one each for FEC12 and FEC34.||Publication Type:||Conference Publication||Conference Name:||16th Conference of the Association for the Advancement of Animal Breeding and Genetics, Noosa Lakes, Australia , 25th September - 28th September, 2005||Conference Details:||16th Conference of the Association for the Advancement of Animal Breeding and Genetics, Noosa Lakes, Australia , 25th September - 28th September, 2005||Source of Publication:||Application of new genetic technologies to animal breeding: Proceedings of the 16th Conference of the Association for the Advancement of Animal Breeding and Genetics, p. 115-118||Publisher:||CSIRO Publishing||Place of Publication:||Collingwood, Australia||ISSN:||1328-3227||Field of Research (FOR):||070201 Animal Breeding||Socio-Economic Outcome Codes:||830311 Sheep - Wool||Peer Reviewed:||Yes||HERDC Category Description:||E1 Refereed Scholarly Conference Publication||Other Links:||http://www.aaabg.org/livestocklibrary/2005/115marshall.pdf
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|Appears in Collections:||Animal Genetics and Breeding Unit (AGBU)|
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