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https://hdl.handle.net/1959.11/4215
Title: | Synchrotron supported DEI/KES of a brain tumor in an animal model: The search for a microimaging modality | Contributor(s): | Mannan, K A (author); Schulltke, E (author); Chapman, D (author); Rigon, L (author); Griebel, R W (author); Menk, R H (author); Siu, K (author); Pavlov, Konstantin M (author) ; Kelly, M (author); McLoughlin, G (author); Beveridge, T (author); Tromba, G (author); Juurlink, B H (author) | Publication Date: | 2005 | DOI: | 10.1016/j.nima.2005.03.075 | Handle Link: | https://hdl.handle.net/1959.11/4215 | Abstract: | Glioblastoma multiforme (GBM) is the commonest and most aggressive primary brain tumor in humans. The high rate of tumor recurrence results in a poor prognosis despite multimodality treatment. One reason for high rate of recurrence is the invasive nature of the tumor into the surrounding normal brain tissue or multifocal occurrence at sites remote from that of the primary tumor establishment. Existing imaging demonstrates the primary tumor but fail to show the residual tumor microaggregates left behind following initial treatment. In this study, we employed diffraction-enhanced imaging (DEI) in an attempt to find an imaging modality that will provide visualization of residual disease that is not be apparent on MRI or CT scans. | Publication Type: | Journal Article | Source of Publication: | Nuclear Instruments & Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment, 548(1-2), p. 106-110 | Publisher: | Elsevier BV | Place of Publication: | Netherlands | ISSN: | 1872-9576 0168-9002 |
Fields of Research (FoR) 2008: | 110904 Neurology and Neuromuscular Diseases 020504 Photonics, Optoelectronics and Optical Communications 110320 Radiology and Organ Imaging |
Socio-Economic Objective (SEO) 2008: | 861503 Scientific Instruments 861502 Medical Instruments |
Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal |
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Appears in Collections: | Journal Article |
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