Fine mapping QTL with haplotypes determined from dense single nucleotide polymorphic markers

Author(s)
Zhang, Yuandan
Tier, Bruce
Hawken, Rachel
Publication Date
2007
Abstract
We use publicly available methods to impute missing genotypes, infer haplotypes and partition haplotypes into blocks for large numbers of single nucleotide polymorphic data on two sections of chromosomes. Haplotype trend regression was used to associate these haplotype blocks with a continuously distributed trait. A number of significant regions of chromosomes, that were not found when tested with single-marker tests, were identified. This study demonstrated a feasible framework to fine-mapping QTL using haplotypes of SNP markers.
Citation
Proceedings of the Association for the Advancement of Animal Breeding and Genetics, v.17, p. 119-122
ISBN
1921208139
ISSN
1328-3227
Link
https://hdl.handle.net/1959.11/4128
Language
en
Publisher
Association for the Advancement of Animal Breeding and Genetics (AAABG)
Title
Fine mapping QTL with haplotypes determined from dense single nucleotide polymorphic markers
Type of document
Conference Publication
Entity Type
Publication

Files:

NameSizeformatDescriptionLink