Light-dependent development of asymmetry in the ipsilateral and contralateral thalamofugal visual projections of the chick

Title
Light-dependent development of asymmetry in the ipsilateral and contralateral thalamofugal visual projections of the chick
Publication Date
2003
Author(s)
Koshiba, Mamiko
Nakamura, Shun
Deng, Chao
Rogers, Lesley
Type of document
Journal Article
Language
en
Entity Type
Publication
Publisher
Elsevier Ireland Ltd
Place of publication
Ireland
DOI
10.1016/S0304-3940(02)01162-X
UNE publication id
une:3737
Abstract
Light-exposure of the chick embryo induces development of asymmetry in the thalamofugal visual projections to the Wulst regions of the forebrain since the embryo is turned so that it occludes its left and not its right eye. This asymmetry can be reversed by occluding the embryo's right eye and exposing its left eye to light. Here we show that three sub-regions of the thalamus (two in the dorsolateral anterior thalami (DLA) and one more caudal) have differing asymmetries of contralateral and/or ipsilateral projections. Hence the effect of asymmetrical light stimulation is regionally specific within the thalamus. Lateralised light stimulation appears to promote the development of ipsilateral projections from DLA pars dorsolateralis pars anterioris and contralateral projections from the caudal regions (the nucleus superficialis parvocellularis especially) but it may suppress the development of contralateral projections from the nucleus dorsolateralis anterior thalami pars lateralis rostralis. We also show that the light stimulation causes lateralised expression of c-fos and receptors for neurotransmitters.
Link
Citation
Neuroscience Letters, 336(0), p. 81-84
ISSN
1872-7972
0304-3940
Start page
81
End page
84

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