In vitro inhibitory activities of sugarcane extract on avian Eimeria sporozoites

Title
In vitro inhibitory activities of sugarcane extract on avian Eimeria sporozoites
Publication Date
2021-12
Author(s)
Daneshmand, Ali
Young, Petrina
Campbell, Bronwyn
Kheravii, Sarbast K
Sharma, Nishchal Kumar
( author )
OrcID: https://orcid.org/0000-0002-8013-9269
Email: nsharma4@une.edu.au
UNE Id une-id:nsharma4
Afshari, Roya
Dias, Daniel A
Flavel, Matthew
Kitchen, Barry
Wu, Shu-Biao
( author )
OrcID: https://orcid.org/0000-0002-1790-6015
Email: swu3@une.edu.au
UNE Id une-id:swu3
Type of document
Journal Article
Language
en
Entity Type
Publication
Publisher
Elsevier Ltd
Place of publication
United Kingdom
DOI
10.1016/j.ijpddr.2021.07.001
UNE publication id
une:1959.11/31058
Abstract
The current in vitro study aimed to investigate the effects of a processed sugarcane extract on the viability of avian Eimeria sporozoites. Treatments were applied to hatched sporozoites: 1) without additives (no-treatment control); 2) with ethanol; 3) with salinomycin; 4) with Polygain™. All treatments were incubated in RPMI media containing live sporozoites at 37°C for 14 h and then the number of viable sporozoites were counted. Compared to the no-treatment control, Polygain™ decreased (P < 0.001) the counts of E. maxima, E. acervulina, E. bruneti, and E. mitis sporozoites to a level similar to salinomycin (P > 0.05). In conclusion, Polygain™ could be a potential candidate as an anticoccidial agent.
Link
Citation
International Journal for Parasitology: Drugs and Drug Resistance, v.17, p. 1-4
ISSN
2211-3207
Start page
1
End page
4
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International

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