Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/31015
Title: A genomic scan for detection of selection signatures using snp data in Australian merino sheep
Contributor(s): Montazeri, M (author); Asadi Fozi, M (author); Esmaeilizadeh Koshkoieh, A (author); Ferdosi, M H  (author)orcid ; van Der Werf, J  (author)orcid 
Publication Date: 2016
Open Access: Yes
Handle Link: https://hdl.handle.net/1959.11/31015
Open Access Link: http://mg.genetics.ir/browse.php?mag_id=146&slc_lang=en&sid=1Open Access Link
Abstract: Deciphering the genetic basis of phenotypic diversity is one of the main aims of biological research. Domestic animals are useful tool for making substantial progress towards this goal. Selection signatures are the regions of the genome that are functionally important and therefore have been under either natural or artificial selection. In this paper, a whole genome scan was performed using 3000 individuals, ~50000 SNP markers from nine populations of Australian Merino sheep, with the aim of identifying divergently selected regions of the genome. Five genomic regions on 4 chromosomes were identified as putatively harboring selective sweeps. These regions were located on chromosomes 6, 7, 11 (two areas) and 26. These selected genomic regions were surveyed to find encoding putative candidate genes and 9 genes were extracted from areas Ovine Genome v3.1 Assembly.Study of the reported QTL in these regions of the sheep genome showed that they overlapped with QTL of economically important traits such as carcass yield, growth and wool traits. Further investigation of these regions in validation studies will help to identify the candidate genes for economically important traits in sheep breeds.
Publication Type: Journal Article
Source of Publication: Modern Genetics Journal, 11(3), p. 459-467
Publisher: Iranian Society of Genetics
Place of Publication: Islamic Republic of Iran
ISSN: 2008-4439
Fields of Research (FoR) 2020: 300305 Animal reproduction and breeding
Socio-Economic Objective (SEO) 2020: 100413 Sheep for wool
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
Publisher/associated links: http://mg.genetics.ir/index.php?&slct_pg_id=10&sid=1&slc_lang=en
Appears in Collections:Animal Genetics and Breeding Unit (AGBU)
Journal Article
School of Environmental and Rural Science

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