Please use this identifier to cite or link to this item:
Title: Hormonal changes, semen quality and variance in reproductive activity outcomes of post pubertal rabbits fed Moringa oleifera Lam. leaf powder
Contributor(s): Ajuogu, Peter Kelechi (author); Mgbere, Osaro O (author); Bila, Disere S (author); McFarlane, James R  (author)orcid 
Publication Date: 2019-04-06
DOI: 10.1016/j.jep.2018.12.036
Handle Link:

Ethnopharmacological relevance: Moringa oleifera Lam. (Moringaceae) is an important plant based staple food, known for its nutritional and medicinal value and is usually prescribed by herbal practitioners in Nigeria and in other tropical countries for the treatment of male infertility problems and reproductive diseases in females. Although the aphrodisiac properties and fertility enhancement potential in males have been reported, the underlying mechanisms for the activity remain unclear. In this study, we investigated the influence of supplementing the diet with M. oleifera Lam. leaf powder on reproductive hormones and semen quality of New Zealand White (NZW) rabbits.

Materials and Methods: Thirty-two (32) NZW rabbits of 50:50 ratio bucks to does, were randomly distributed to four treatment groups (n = 4 bucks, n = 4 does per group). Graded levels (0, 5, 10 and 15 g/kg) of M. oleifera Lam. leaf powder was incorporated into rabbit growers pellet. The does and bucks were housed separately in hutches and sheltered under the same environmental conditions with free access to their respective treatment diets for a period of 12 weeks.

Results: In female rabbits, treatment revealed significant (P < 0.05) dose-dependent reduction in the concentration of serum FSH, LH and oestrogen. While in contrast the highest dose of leaf powder significantly (P < 0.05) increased progesterone and prolactin concentrations remained unaffected. On the other hand, the concentration of FSH and LH in bucks was significantly (P < 0.05) increased in treatment groups compared to the control group. Serum testosterone concentrations were significantly lower in the 5 and 10 g/kg treatment groups. Semen volume, sperm count and motility were significantly improved in a dose dependent manner with increasing amounts of M. oleifera Lam. leaf powder in the diet

Conclusions: We conclude that M. oleifera Lam. leaf powder supplementation to the diet was more beneficial to male rabbit fertility than the female, where it tended to have a negative impact through the hypothalamic-pituitary-gonadal axis. However, with the varying impact of M. oleifera Lam. leaf powder on the hypothalamic-pituitary-gonadal axis of male and female animals, further investigation is necessary to determine the mechanism through which it operates.

Publication Type: Journal Article
Source of Publication: Journal of Ethnopharmacology, v.233, p. 80-86
Publisher: Elsevier Ireland Ltd
Place of Publication: Ireland
ISSN: 1872-7573
Fields of Research (FoR) 2008: 070206 Animal Reproduction
110499 Complementary and Alternative Medicine not elsewhere classified
070204 Animal Nutrition
Fields of Research (FoR) 2020: 300305 Animal reproduction and breeding
300303 Animal nutrition
Socio-Economic Objective (SEO) 2008: 839999 Animal Production and Animal Primary Products not elsewhere classified
920114 Reproductive System and Disorders
920411 Nutrition
Socio-Economic Objective (SEO) 2020: 200410 Nutrition
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
Appears in Collections:Journal Article
School of Science and Technology

Files in This Item:
1 files
File SizeFormat 
Show full item record


checked on Sep 9, 2023

Page view(s)

checked on Mar 7, 2023


checked on Mar 7, 2023
Google Media

Google ScholarTM



Items in Research UNE are protected by copyright, with all rights reserved, unless otherwise indicated.