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https://hdl.handle.net/1959.11/28980
Title: | Genomic prediction based on selected variants from imputed whole-genome sequence data in Australian sheep populations | Contributor(s): | Moghaddar, Nasir (author) ; Khansefid, Majid (author); van der Werf, Julius H J (author) ; Bolormaa, Sunduimijid (author); Duijvesteijn, Naomi (author); Clark, Samuel A (author) ; Swan, Andrew A (author) ; Daetwyler, Hans D (author); MacLeod, Iona M (author) | Publication Date: | 2019-12-05 | Open Access: | Yes | DOI: | 10.1186/s12711-019-0514-2 | Handle Link: | https://hdl.handle.net/1959.11/28980 | Abstract: | Background: Whole-genome sequence (WGS) data could contain information on genetic variants at or in high linkage disequilibrium with causative mutations that underlie the genetic variation of polygenic traits. Thus far, genomic prediction accuracy has shown limited increase when using such information in dairy cattle studies, in which one or few breeds with limited diversity predominate. The objective of our study was to evaluate the accuracy of genomic prediction in a multi-breed Australian sheep population of relatively less related target individuals, when using information on imputed WGS genotypes. | Publication Type: | Journal Article | Source of Publication: | Genetics Selection Evolution, 51(1), p. 1-14 | Publisher: | BioMed Central Ltd | Place of Publication: | United Kingdom | ISSN: | 1297-9686 0999-193X |
Fields of Research (FoR) 2008: | 070201 Animal Breeding 060412 Quantitative Genetics (incl. Disease and Trait Mapping Genetics) 060408 Genomics |
Fields of Research (FoR) 2020: | 300305 Animal reproduction and breeding 310506 Gene mapping 310509 Genomics |
Socio-Economic Objective (SEO) 2008: | 830310 Sheep - Meat 830311 Sheep - Wool |
Socio-Economic Objective (SEO) 2020: | 100412 Sheep for meat 100413 Sheep for wool |
Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal | Description: | Supplementary information accompanies this paper at https://doi.org/10.1186/s12711-019-0514-2 |
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Appears in Collections: | Animal Genetics and Breeding Unit (AGBU) Journal Article School of Environmental and Rural Science |
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openpublished/GenomicMoghaddarVanDerWerfDuijvesteijnClarkSwan2019JournalArticle.pdf | Published version | 3.32 MB | Adobe PDF Download Adobe | View/Open |
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