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https://hdl.handle.net/1959.11/28968
Title: | How robust are genomic selection methods? | Contributor(s): | Clark, S A (author)![]() ![]() |
Publication Date: | 2010 | Handle Link: | https://hdl.handle.net/1959.11/28968 | Abstract: | Genomic information from many single nucleotide polymorphism (SNP) markers can be used to increase the accuracy of estimated breeding values of young animals. This is termed genomic selection (GS) and is based on prediction of the effects of quantitative trait loci (QTL) in linkage disequilibrium (LD) with markers (Meuwissen et al. 2001). However, Habier et al. (2007) proposed that GS also relies on “relationships” between individuals to accurately predict genetic value. A better understanding of what GS actually predicts is needed to develop marker panels, training populations and methods for accurately estimating breeding values. The efficacy of methods used to predict genomic breeding value may depend on the underlying model of genetic variation, which is not well known. The aim of this study was to determine the accuracy and robustness of various methods used for genomic selection using a range of underlying genetic models and to compare the accuracy of GS when predicting one generation ahead (training set 1), several generations ahead (training set 2) or across different populations (training set 3). | Publication Type: | Conference Publication | Conference Details: | Sheep CRC 2010: Sheep CRC Research Conference: Transforming Wool, Meat & the Sheep that produce them, Adelaide, Australia, 20th - 21st October, 2010 | Source of Publication: | Sheep CRC 2010 Conference Proceedings | Publisher: | Sheep CRC | Place of Publication: | Armidale, Australia | Fields of Research (FoR) 2008: | 070201 Animal Breeding 060412 Quantitative Genetics (incl. Disease and Trait Mapping Genetics) 060408 Genomics |
Socio-Economic Objective (SEO) 2008: | 830310 Sheep - Meat | HERDC Category Description: | E2 Non-Refereed Scholarly Conference Publication | Publisher/associated links: | http://www.livestocklibrary.com.au/bitstream/handle/1234/35481/SheepCRC_31_22.pdf?sequence=1 |
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Appears in Collections: | Conference Publication School of Environmental and Rural Science |
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