Diterpene and flavonoid constituents of the newly identified Australian Olearia sp. Munro State Forest

Title
Diterpene and flavonoid constituents of the newly identified Australian Olearia sp. Munro State Forest
Publication Date
2020
Author(s)
Greatrex, Ben
( creator )
OrcID: https://orcid.org/0000-0002-0356-4966
Email: bgreatre@une.edu.au
UNE Id une-id:bgreatre
Ozga, Theo
Lyddiard, Dane
Type of document
Dataset
Language
en
Entity Type
Publication
Publisher
University of New England
Place of publication
Armidale, Australia
DOI
10.25952/5ecb38be46997
UNE publication id
une:1959.11/28775
Abstract
The phytochemistry and antimicrobial activity of the newly identified Australian plant Olearia sp. Munro State Forest was examined. Antimicrobial TLC bioautography-guided isolation followed by NMR spectroscopy was used to identify the known compounds 8-O-β-D-xylopyranosyl-ent-8β-hydroxylabdan-15-oic acid (1) and pinocembrin (7), and new compounds 8-O-β-D-xylopyranosyl-ent-labdan-8β,15-diol (2) and ent-15-hydroxyclerod-3-en-17-oic acid (4a). Compounds without apparent activity in TLC bioautography included the previously undescribed ent-clerod-3-en-15,17-dioic acid (3a) and ent-cleroda-3,13-dien-15,17-dioic acid (5a), as well as known ent-8β-hydroxylabdan-15-oic acid (6) and penduletin (8). This is the first phytochemical and antibacterial study on this species of Olearia and has shown it to be an abundant source of ent-labdanes and ent-clerodanes.
Link
Rights
Attribution 4.0 International

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opendataset/NMR_data_Olearia_sp.zip 154930.898 KB NMR data files for Olearia sp. Munro State Forest View document