Heffernan, Megan

Andrews, Gavin

Fiatarone Singh, Maria A

Valenzuela, Michael

Anstey, Kaarin J

Maeder, Anthony J

McNeil, John

Jorm, Louisa

Lautenschlager, Nicola T

Sachdev, Perminder S

Ginige, Jeewani A

Hobbs, Megan J

Boulamatsis, Christos

Chau, Tiffany

Cobiac, Lynne

Cox, Kay L

Daniel, Kenneth

Flood, Victoria M

Guerrero, Yareni

Gunn, Jane

Jain, Nidhi

Kochan, Nicole A

Lampit, Amit

Mavros, Yorgi

Meiklejohn, Jacinda

Noble, Yian

O'Leary, Fiona

Radd-Vagenas, Sue

Walton, Courtney C

Bosler, Nan

Betz-Stablein, Brigid

Briggs, Nancy

Christensen, Helen

Chuprov, Igor

Hayen, Andrew

Kivipelto, Miia

Lapsley, Helen

Redman, Sally

San Jose, Juan Carlo

Welberry, Heidi

Brodaty, Henry

2019-08-13

Background: Maintain Your Brain (MYB) is a randomized controlled trial of an online multi-modal lifestyle intervention targeting modifiable dementia risk factors with its primary aim being to reduce cognitive decline in an older age cohort. Methods: MYB aims to recruit 8,500 non-demented community dwelling 55 to 77 year olds from the Sax Institute’s 45 and Up Study in New South Wales, Australia. Participants will be screened for risk factors related to four modules that comprise the MYB intervention: physical activity, nutrition, mental health, and cognitive training. Targeting risk factors will enable interventions to be personalized so that participants receive the most appropriate modules. MYB will run for three years and up to four modules will be delivered sequentially each quarter during year one. Upon completing a module, participants will continue to receive less frequent booster activities for their eligible modules (except for the mental health module) until the end of the trial. Discussion: MYB will be the largest internet-based trial to attempt to prevent cognitive decline and potentially dementia. If successful, MYB will provide a model for not just effective intervention among older adults, but an intervention that is scalable for broad use.

Journal of Alzheimer's Disease, 70(s1), p. S221-S237

1875-8908

1387-2877

30475762

https://hdl.handle.net/1959.11/28728

en

IOS Press

Attribution-NonCommercial 4.0 International

Maintain Your Brain: Protocol of a 3-Year Randomized Controlled Trial of a Personalized Multi-Modal Digital Health Intervention to Prevent Cognitive Decline Among Community Dwelling 55 to 77 Year Olds

Journal Article

Publication