Genetic Structure and Differentiation Among African Bos Taurus Cattle Breeds

Gebrehiwot, N Z; Strucken, E M; Aliloo, H; Marshall, K; Gibson, J P

Author(s)

Gebrehiwot, N Z

Strucken, E M

Aliloo, H

Marshall, K

Gibson, J P

Publication Date

2019

Abstract

African taurine cattle populations are widely distributed in humid and sub-humid zones of West and Central Africa. We assessed the genetic structure and differentiation within and across 8 African Bos taurus populations: 4 N’Dama populations (N’Dama, N’Dama1, N’Dama2, N’Dama3), Lagunaire, Lagune, Somba, and Baoule. A total of 38k autosomal SNPs were used for principal component analyses (PCA), estimation of pairwise FST values and within population heterozygosity (FIS), and neighbour-joining (NJ) tree construction. The first PC clearly differentiated Lagune and Lagunaire from N’Dama; PC2 separated Lagunaire, Lagune and one N’Dama population from the rest of taurine breeds; and PC3 separated N’Dama3 from Somba and Baoule. Estimates of pairwise FST values among the majority of populations ranged from 0.03 to 0.149, indicating low to moderate genetic differentiations, while a high genetic divergence between N’Dama3 and Lagune (FST =0.178), and N’Dama3 and Lagunaire (FST =0.168) was observed. No genetic subdivision was found between N’Dama and N’Dama1, and Lagune and Lagunaire. A higher heterozygosity (FIS value from -0.011 to 0.025) was found in N’Dama, N’Dama1, N’Dama2, Lagune, Lagunaire, and Baoule breeds. The NJ tree clearly separated Lagune and Lagunaire as well as Somba and Baoule with a 100% and around 31% bootstrap value, respectively, from the other taurine populations. We highlighted that African taurine populations are diverse and genetic differences between sampling locations exists even within a breed. Therefore, choice of an African taurine breed to anchor African indigenous breeds should be carefully considered.

Citation

Proceedings of the Association for the Advancement of Animal Breeding and Genetics, v.23, p. 179-182

ISSN

1328-3227

Link

https://hdl.handle.net/1959.11/28679

Language

en

Publisher

Association for the Advancement of Animal Breeding and Genetics (AAABG)

Title

Genetic Structure and Differentiation Among African Bos Taurus Cattle Breeds

Type of document

Conference Publication

Entity Type

Publication

Author(s)	Gebrehiwot, N Z Strucken, E M Aliloo, H Marshall, K Gibson, J P
Publication Date	2019
Abstract	African taurine cattle populations are widely distributed in humid and sub-humid zones of West and Central Africa. We assessed the genetic structure and differentiation within and across 8 African Bos taurus populations: 4 N’Dama populations (N’Dama, N’Dama1, N’Dama2, N’Dama3), Lagunaire, Lagune, Somba, and Baoule. A total of 38k autosomal SNPs were used for principal component analyses (PCA), estimation of pairwise FST values and within population heterozygosity (FIS), and neighbour-joining (NJ) tree construction. The first PC clearly differentiated Lagune and Lagunaire from N’Dama; PC2 separated Lagunaire, Lagune and one N’Dama population from the rest of taurine breeds; and PC3 separated N’Dama3 from Somba and Baoule. Estimates of pairwise FST values among the majority of populations ranged from 0.03 to 0.149, indicating low to moderate genetic differentiations, while a high genetic divergence between N’Dama3 and Lagune (FST =0.178), and N’Dama3 and Lagunaire (FST =0.168) was observed. No genetic subdivision was found between N’Dama and N’Dama1, and Lagune and Lagunaire. A higher heterozygosity (FIS value from -0.011 to 0.025) was found in N’Dama, N’Dama1, N’Dama2, Lagune, Lagunaire, and Baoule breeds. The NJ tree clearly separated Lagune and Lagunaire as well as Somba and Baoule with a 100% and around 31% bootstrap value, respectively, from the other taurine populations. We highlighted that African taurine populations are diverse and genetic differences between sampling locations exists even within a breed. Therefore, choice of an African taurine breed to anchor African indigenous breeds should be carefully considered.
Citation	Proceedings of the Association for the Advancement of Animal Breeding and Genetics, v.23, p. 179-182
ISSN	1328-3227
Link	https://hdl.handle.net/1959.11/28679
Language	en
Publisher	Association for the Advancement of Animal Breeding and Genetics (AAABG)
Title	Genetic Structure and Differentiation Among African Bos Taurus Cattle Breeds
Type of document	Conference Publication
Entity Type	Publication

Genetic Structure and Differentiation Among African Bos Taurus Cattle Breeds

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