Investigation into the Effects of Number of SNPs and Number of Reference Individuals on Imputation Accuracy

Author(s)
Ferdosi, M H
Connors, N K
Publication Date
2019
Abstract
Imputation is used in Australia’s national beef genetic evaluation, BREEDPLAN, to resolve missing genomic information in the combined panels of genomic data and clarify relationships through building a genomic relationship matrix (GRM). The accuracy of imputation is dependent on many factors such as the size of reference population and the density of markers. Here we demonstrated an improvement in imputation accuracy of Angus genotypes by increasing the numbers of individuals and the density of markers in the reference population. The results show a considerable increase in imputation accuracy by increasing density of markers up to 15k SNPs.
Citation
Proceedings of the Association for the Advancement of Animal Breeding and Genetics, v.23, p. 480-483
ISSN
1328-3227
Link
https://hdl.handle.net/1959.11/28674
Language
en
Publisher
Association for the Advancement of Animal Breeding and Genetics (AAABG)
Title
Investigation into the Effects of Number of SNPs and Number of Reference Individuals on Imputation Accuracy
Type of document
Conference Publication
Entity Type
Publication

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