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Title: Genome-wide association study of first lambing age and lambing interval in sheep
Contributor(s): Abdoli, R (author); Mirhoseini, S Z (author); Ghavi Hossein-Zadeh, N (author); Zamani, P (author); Moradi, M H (author); Ferdosi, M H  (author)orcid ; Gondro, C (author)
Publication Date: 2019-09
Early Online Version: 2019-07-26
DOI: 10.1016/j.smallrumres.2019.07.014
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Abstract: First lambing age and lambing interval are among the most important reproductive traits affecting profitability of sheep breeding systems. Genome-wide association studies (GWAS) were performed on estimated breeding values (EBVs) for age at first lambing and the lambing interval between first and second lambing in Lori-Bakhtiari ewes. Animals were genotyped using the Illumina Ovine SNP50 K genotyping array. Two single nucleotide polymorphisms (SNPs) associated with lambing interval were identified on chromosomes 1 and 2 (Bonferroni adjusted P-value<0.05). No SNP associated with first lambing age was detected. SNP s50067.1 on sheep chromosome 2:86798921 is within a candidate gene; ADAMTS like 1 (ADAMTSL1), known to be involved in proteolysis, peptidase activity, biological process and reproductive pathways in mammalian species. No candidate gene was detected for SNP OAR1_57568179.1 on chromosome 1. The results of the present study may provide new insights into the genomic regions involved in reproductive traits of sheep.
Publication Type: Journal Article
Source of Publication: Small Ruminant Research, v.178, p. 43-45
Publisher: Elsevier BV
Place of Publication: Netherlands
ISSN: 0921-4488
Fields of Research (FoR) 2008: 070201 Animal Breeding
Fields of Research (FoR) 2020: 300305 Animal reproduction and breeding
Socio-Economic Objective (SEO) 2008: 830310 Sheep - Meat
Socio-Economic Objective (SEO) 2020: 100412 Sheep for meat
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
Appears in Collections:Animal Genetics and Breeding Unit (AGBU)
Journal Article

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