Please use this identifier to cite or link to this item:
https://hdl.handle.net/1959.11/26664
Title: | Supervised, but Not Home-Based, Isometric Training Improves Brachial and Central Blood Pressure in Medicated Hypertensive Patients: A Randomized Controlled Trial | Contributor(s): | Farah, Breno Q (author); Rodrigues, Sergio L C (author); Silva, Gustavo O (author); Pedrosa, Rodrigo P (author); Correia, Marilia A (author); Barros, Mauro V G (author); Deminice, Rafael (author); Marinello, Poliana C (author); Smart, Neil A (author) ; Vianna, Lauro C (author); Ritti-Dias, Raphael M (author) | Publication Date: | 2018-07-23 | Open Access: | Yes | DOI: | 10.3389/fphys.2018.00961 | Handle Link: | https://hdl.handle.net/1959.11/26664 | Abstract: | Meta-analyses have shown that supervised isometric handgrip training reduces blood pressure in hypertensives. However, the mechanism(s) underlying these effects in medicated hypertensive patients, as well as the effects from home-based exercise training, is uncertain. The purpose of this study was to compare the effects of supervised and home-based isometric handgrip training on cardiovascular parameters in medicated hypertensives. In this randomized controlled trial, 72 hypertensive individuals (38–79 years old, 70% female) were randomly assigned to three groups: home-based, supervised isometric handgrip training or control groups. Home-based and supervised isometric handgrip training was completed thrice weekly (4 × 2 min at 30% of maximal voluntary contraction, with 1-min rest between bouts, alternating the hands). Before and after 12 weeks brachial, central and ambulatory blood pressures (BP), arterial stiffness, heart rate variability, vascular function, oxidative stress and inflammation markers were obtained. No significant ( > 0.05) effect was observed for ambulatory BP, arterial stiffness, heart rate variability, vascular function and oxidative stress and inflammatory markers in all three groups. Brachial BP decreased in the supervised group (Systolic: 132 ± 4 vs. 120 ± 3 mmHg; Diastolic: 71 ± 2 vs. 66 ± 2 mmHg, p < 0.05), whereas no significant differences were observed in the home-based (Systolic: 130 ± 4 vs. 126 ± 3 mmHg; diastolic: 73 ± 3 vs. 71 ± 3 mmHg) and control groups ( > 0.05). Supervised handgrip exercise also reduced central BP systolic (120 ± 5 vs. 109 ± 5 mmHg), diastolic (73 ± 2 vs. 67 ± 2 mmHg); and mean BP (93 ± 3 vs. 84 ± 3 mmHg), whereas no significant effects were found in the home-based (Systolic: 119 ± 4 vs. 115 ± 3 mmHg; Diastolic: 74 ± 3 vs. 71 ± 3 mmHg) and control groups ( > 0.05). In conclusion, supervised, but not home-based, isometric training lowered brachial and central BP in hypertensives. | Publication Type: | Journal Article | Source of Publication: | Frontiers in Physiology, v.9, p. 1-10 | Publisher: | Frontiers Research Foundation | Place of Publication: | Switzerland | ISSN: | 1664-042X | Fields of Research (FoR) 2008: | 110602 Exercise Physiology 110299 Cardiorespiratory Medicine and Haematology not elsewhere classified |
Fields of Research (FoR) 2020: | 320101 Cardiology (incl. cardiovascular diseases) | Socio-Economic Objective (SEO) 2008: | 920103 Cardiovascular System and Diseases | Socio-Economic Objective (SEO) 2020: | 200101 Diagnosis of human diseases and conditions | Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal |
---|---|
Appears in Collections: | Journal Article School of Science and Technology |
Files in This Item:
File | Description | Size | Format |
---|
SCOPUSTM
Citations
30
checked on Apr 13, 2024
Page view(s)
1,636
checked on Oct 22, 2023
This item is licensed under a Creative Commons License