Advantages of breast cancer visualization and characterization using synchrotron radiation phase-contrast tomography

Title
Advantages of breast cancer visualization and characterization using synchrotron radiation phase-contrast tomography
Publication Date
2018
Author(s)
Pacile, Serena
Baran, Patrycja
Dullin, Christian
Dimmock, Matthew
Lockie, Darren
Missbach-Guntner, Jeannine
Quiney, Harry
McCormack, Mikkaela
Mayo, Sheridan
Thompson, Darren
Nesterets, Yakov
Hall, Chris
Pavlov, Konstantin
( author )
OrcID: https://orcid.org/0000-0002-1756-4406
Email: kpavlov@une.edu.au
UNE Id une-id:kpavlov
Prodanovic, Zdenka
Tonutti, Maura
Accardo, Agostino
Fox, Jane
Tavakoli Taba, Seyedamir
Lewis, Sarah
Brennan, Patrick
Hausermann, Daniel
Tromba, Giuliana
Gureyev, Tim
( author )
OrcID: https://orcid.org/0000-0002-1103-0649
Email: tgureyev@une.edu.au
UNE Id une-id:tgureyev
Type of document
Journal Article
Language
en
Entity Type
Publication
Publisher
Wiley-Blackwell Publishing Ltd
Place of publication
United Kingdom
DOI
10.1107/S1600577518010172
UNE publication id
une:1959.11/26567
Abstract
The aim of this study was to highlight the advantages that propagation-based phase-contrast computed tomography (PB-CT) with synchrotron radiation can provide in breast cancer diagnostics. For the first time, a fresh and intact mastectomy sample from a 60 year old patient was scanned on the IMBL beamline at the Australian Synchrotron in PB-CT mode and reconstructed. The clinical picture was described and characterized by an experienced breast radiologist, who underlined the advantages of providing diagnosis on a PB-CT volume rather than conventional two-dimensional modalities. Subsequently, the image quality was assessed by 11 breast radiologists and medical imaging experts using a radiological scoring system. The results indicate that, with the radiation dose delivered to the sample being equal, the accuracy of a diagnosis made on PB-CT images is significantly higher than one using conventional techniques.
Link
Citation
Journal of Synchrotron Radiation, 25(5), p. 1460-1466
ISSN
1600-5775
0909-0495
Start page
1460
End page
1466

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