Please use this identifier to cite or link to this item:
https://hdl.handle.net/1959.11/23562
Title: | Bronchiectasis in indigenous and non-indigenous residents of Australia and New Zealand | Contributor(s): | Blackall, Sean R (author); Hong, Jae B (author); King, Paul (author); Wong, Conroy (author); Einsiedel, Lloyd (author); Rémond, Marc G W (author); Woods, Cindy (author)![]() |
Publication Date: | 2018 | DOI: | 10.1111/resp.13280 | Handle Link: | https://hdl.handle.net/1959.11/23562 | Abstract: | Background and objective: Bronchiectasis not associated with cystic fibrosis is an increasingly recognized chronic lung disease. In Oceania, indigenous populations experience a disproportionately high burden of disease. We aimed to describe the natural history of bronchiectasis and identify risk factors associated with premature mortality within a cohort of Aboriginal Australians, New Zealand Māori and Pacific Islanders, and non-indigenous Australians and New Zealanders. Methods: This was a retrospective cohort study of bronchiectasis patients aged >15 years at three hospitals: Alice Springs Hospital and Monash Medical Centre in Australia, and Middlemore Hospital in New Zealand. Data included demographics, ethnicity, sputum microbiology, radiology, spirometry, hospitalization and survival over 5 years of follow-up. Results: Aboriginal Australians were significantly younger and died at a significantly younger age than other groups. Age- and sex-adjusted all-cause mortality was higher for Aboriginal Australians (hazard ratio (HR): 3.9), and respiratory-related mortality was higher for both Aboriginal Australians (HR: 4.3) and Māori and Pacific Islander people (HR: 1.7). Hospitalization was common: Aboriginal Australians had 2.9 admissions/person-year and 16.9 days in hospital/person-year. Despite Aboriginal Australians having poorer prognosis, calculation of the FACED score suggested milder disease in this group. Sputum microbiology varied with Aspergillus fumigatus more often isolated from non-indigenous patients. Airflow obstruction was common (66.9%) but not invariable. Conclusions: Bronchiectasis is not one disease. It has a significant impact on healthcare utilization and survival. Differences between populations are likely to relate to differing aetiologies and understanding the drivers of bronchiectasis in disadvantaged populations will be key. | Publication Type: | Journal Article | Source of Publication: | Respirology, 23(8), p. 743-749 | Publisher: | Wiley-Blackwell Publishing Asia | Place of Publication: | Australia | ISSN: | 1440-1843 1323-7799 |
Fields of Research (FoR) 2008: | 111099 Nursing not elsewhere classified | Fields of Research (FoR) 2020: | 420202 Disease surveillance 450406 Aboriginal and Torres Strait Islander epidemiology 451005 Te mātai tahumaero o te Māori (Māori epidemiology) |
Socio-Economic Objective (SEO) 2008: | 920302 Aboriginal and Torres Strait Islander Health - Health Status and Outcomes 920305 Maori Health - Health Status and Outcomes |
Socio-Economic Objective (SEO) 2020: | 210302 Aboriginal and Torres Strait Islander health status and outcomes 210702 Te tūnga me ngā putanga hauora (Māori health status and outcomes) |
Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal |
---|---|
Appears in Collections: | Journal Article School of Health |
Files in This Item:
File | Description | Size | Format |
---|
SCOPUSTM
Citations
46
checked on Aug 17, 2024
Page view(s)
2,624
checked on Apr 28, 2024
Items in Research UNE are protected by copyright, with all rights reserved, unless otherwise indicated.