A Simple Method for Evaluating the Genotype Quality of the Sire X Chromosome Using Half‑Sib Families

Title
A Simple Method for Evaluating the Genotype Quality of the Sire X Chromosome Using Half‑Sib Families
Publication Date
2017
Author(s)
Ferdosi, Mohammad
( author )
OrcID: https://orcid.org/0000-0001-5385-4913
Email: mferdos3@une.edu.au
UNE Id une-id:mferdos3
Johnston, David
( author )
OrcID: https://orcid.org/0000-0002-4995-8311
Email: djohnsto@une.edu.au
UNE Id une-id:djohnsto
Al-Mamun, Hawlader A
Gondro, Cedric
( author )
OrcID: https://orcid.org/0000-0003-0666-656X
Email: cgondro2@une.edu.au
UNE Id une-id:cgondro2
Editor
Editor(s): Laercio Porto-Neto
Type of document
Conference Publication
Language
en
Entity Type
Publication
Publisher
Association for the Advancement of Animal Breeding and Genetics (AAABG)
Place of publication
Armidale, Australia
UNE publication id
une:23635
Abstract
Recent studies have shown that the bovine X chromosome contains more than a thousand genes, some of which may be economically important. However, since males are heterogametic for the X chromosome, it has, to date, largely been ignored for genomic prediction and its information content has not been fully explored. The genotyping quality of the X chromosome is the first question that must be addressed. In this study, we suggest a simple method to impute the X chromosome of the sire using a half-sib family in order to check genotyping accuracy. The results showed that the suggested method allows for a robust imputation of the X chromosome in ungenotyped sires and is useful for the routine quality control of the genomic data.
Link
Citation
Proceedings of the Association for the Advancement of Animal Breeding and Genetics, v.22, p. 421-424
ISSN
1328-3227
Start page
421
End page
424

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