A Simple Method for Evaluating the Genotype Quality of the Sire X Chromosome Using Half‑Sib Families

Author(s)
Ferdosi, Mohammad
Johnston, David
Al-Mamun, Hawlader A
Gondro, Cedric
Publication Date
2017
Abstract
Recent studies have shown that the bovine X chromosome contains more than a thousand genes, some of which may be economically important. However, since males are heterogametic for the X chromosome, it has, to date, largely been ignored for genomic prediction and its information content has not been fully explored. The genotyping quality of the X chromosome is the first question that must be addressed. In this study, we suggest a simple method to impute the X chromosome of the sire using a half-sib family in order to check genotyping accuracy. The results showed that the suggested method allows for a robust imputation of the X chromosome in ungenotyped sires and is useful for the routine quality control of the genomic data.
Citation
Proceedings of the Association for the Advancement of Animal Breeding and Genetics, v.22, p. 421-424
ISSN
1328-3227
Link
Language
en
Publisher
Association for the Advancement of Animal Breeding and Genetics (AAABG)
Title
A Simple Method for Evaluating the Genotype Quality of the Sire X Chromosome Using Half‑Sib Families
Type of document
Conference Publication
Entity Type
Publication

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