Cancer Is Not (Only) a Senescence Problem

Author(s)
Thomas, Frederic
Vavre, Fabrice
Hamede, Rodrigo K
Biro, Peter A
Ujvari, Beata
Tissot, Tazzio
Vittecoq, Marion
Giraudeau, Mathieu
Bernex, Florence
Misse, Dorothee
Renaud, Francois
Raven, Nynke
Beckmann, Christa
Publication Date
2018
Abstract
Age is one of the strongest predictors of cancer and risk of death from cancer. Cancer is therefore generally viewed as a senescence-related malady. However, cancer also exists at subclinical levels in humans and other animals, but its earlier effects on the body are poorly known by comparison. We argue here that cancer is a significant but ignored burden on the body and is likely to be a strong selective force from early during the lifetime of an organism. It is time to adopt this novel view of malignant pathologies to improve our understanding of the ways in which oncogenic phenomena influence the ecology and evolution of animals long before their negative impacts become evident and fatal.
Citation
Trends in Cancer, 4(3), p. 169-172
ISSN
2405-8025
2405-8033
Link
Language
en
Publisher
Cell Press
Title
Cancer Is Not (Only) a Senescence Problem
Type of document
Journal Article
Entity Type
Publication

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