Anti-mycobacterial activity of a bis-sulfonamide

Author(s)
Wilkinson, Brendan
Bornaghi, Laurent F
Wright, Anthony D
Houston, Todd A
Poulsen, Sally-Ann
Publication Date
2007
Abstract
A bis-arylsulfonamide, 7, has been identified that exhibits growth inhibition of Mycobacterium smegmatis at less than 25 μg/mL, but has no such activity against Escherichia coli or Staphylococcus aureus. A closely related bis-arylsulfonamide (8) was much less active, but was the only other compound among 54 arylsulfonamides tested with detectable growth inhibition of M. smegmatis.
Citation
Bioorganic & Medicinal Chemistry Letters, 17(5), p. 1355-1357
ISSN
1464-3405
0960-894X
Link
Language
en
Publisher
Pergamon Press
Title
Anti-mycobacterial activity of a bis-sulfonamide
Type of document
Journal Article
Entity Type
Publication

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