Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/22074
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dc.contributor.authorLee, Sang Hongen
dc.contributor.authorYang, Jianen
dc.contributor.authorWray, Naomi Ren
dc.contributor.authorChen, Guo-Boen
dc.contributor.authorRipke, Stephanen
dc.contributor.authorStahl, Eli Aen
dc.contributor.authorHultman, Christina Men
dc.contributor.authorSklar, Pamelaen
dc.contributor.authorVisscher, Peter Men
dc.contributor.authorSullivan, Patrick Fen
dc.contributor.authorGoddard, Michael Een
dc.date.accessioned2017-10-27T16:59:00Z-
dc.date.issued2013-
dc.identifier.citationAmerican Journal of Human Genetics, 93(6), p. 1151-1155en
dc.identifier.issn1537-6605en
dc.identifier.issn0002-9297en
dc.identifier.urihttps://hdl.handle.net/1959.11/22074-
dc.description.abstractTo the Editor: Recently, Speed et al. undertook a comprehensive and elegant evaluation of five key assumptions underlying the linear mixed model implemented in the program GCTA for estimation of SNP heritability. They concluded that the method is robust to violations of four of the assumptions. However, they found that SNP-heritability estimates were sensitive to uneven linkage disequilibrium (LD) between SNPs (implying uneven tagging of causal variants) and suggested an approach to improving the robustness of estimates in this context.en
dc.languageenen
dc.publisherCell Pressen
dc.relation.ispartofAmerican Journal of Human Geneticsen
dc.titleEstimation of SNP Heritability from Dense Genotype Dataen
dc.typeJournal Articleen
dc.identifier.doi10.1016/j.ajhg.2013.10.015en
dcterms.accessRightsGolden
dc.subject.keywordsGene Expression (incl. Microarray and other genome-wide approaches)en
local.contributor.firstnameSang Hongen
local.contributor.firstnameJianen
local.contributor.firstnameNaomi Ren
local.contributor.firstnameGuo-Boen
local.contributor.firstnameStephanen
local.contributor.firstnameEli Aen
local.contributor.firstnameChristina Men
local.contributor.firstnamePamelaen
local.contributor.firstnamePeter Men
local.contributor.firstnamePatrick Fen
local.contributor.firstnameMichael Een
local.subject.for2008060405 Gene Expression (incl. Microarray and other genome-wide approaches)en
local.subject.seo2008920110 Inherited Diseases (incl. Gene Therapy)en
local.profile.schoolSchool of Environmental and Rural Scienceen
local.profile.emailslee38@une.edu.auen
local.output.categoryC1en
local.record.placeauen
local.record.institutionUniversity of New Englanden
local.identifier.epublicationsrecordune-20171024-17338en
local.publisher.placeHouston, United States of Americaen
local.format.startpage1151en
local.format.endpage1155en
local.peerreviewedYesen
local.identifier.volume93en
local.identifier.issue6en
local.access.fulltextYesen
local.contributor.lastnameLeeen
local.contributor.lastnameYangen
local.contributor.lastnameWrayen
local.contributor.lastnameChenen
local.contributor.lastnameRipkeen
local.contributor.lastnameStahlen
local.contributor.lastnameHultmanen
local.contributor.lastnameSklaren
local.contributor.lastnameVisscheren
local.contributor.lastnameSullivanen
local.contributor.lastnameGoddarden
dc.identifier.staffune-id:slee38en
local.profile.roleauthoren
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local.profile.roleauthoren
local.profile.roleauthoren
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local.profile.roleauthoren
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local.identifier.unepublicationidune:22264en
local.identifier.handlehttps://hdl.handle.net/1959.11/22074en
dc.identifier.academiclevelAcademicen
local.title.maintitleEstimation of SNP Heritability from Dense Genotype Dataen
local.output.categorydescriptionC1 Refereed Article in a Scholarly Journalen
local.search.authorLee, Sang Hongen
local.search.authorYang, Jianen
local.search.authorWray, Naomi Ren
local.search.authorChen, Guo-Boen
local.search.authorRipke, Stephanen
local.search.authorStahl, Eli Aen
local.search.authorHultman, Christina Men
local.search.authorSklar, Pamelaen
local.search.authorVisscher, Peter Men
local.search.authorSullivan, Patrick Fen
local.search.authorGoddard, Michael Een
local.uneassociationUnknownen
local.year.published2013en
local.subject.for2020310505 Gene expression (incl. microarray and other genome-wide approaches)en
local.subject.seo2020200101 Diagnosis of human diseases and conditionsen
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