Is daily replication necessary when sampling cortisol concentrations in association studies of children with autism spectrum disorder? A systematic review and discussion paper

Title
Is daily replication necessary when sampling cortisol concentrations in association studies of children with autism spectrum disorder? A systematic review and discussion paper
Publication Date
2017
Author(s)
Sharpley, Christopher
( author )
OrcID: https://orcid.org/0000-0001-7922-4848
Email: csharpl3@une.edu.au
UNE Id une-id:csharpl3
Bitsika, Vicki
( author )
OrcID: https://orcid.org/0000-0003-2518-6684
Email: vbitsik2@une.edu.au
UNE Id une-id:vbitsik2
Agnew, Linda
( author )
OrcID: https://orcid.org/0000-0002-2803-0995
Email: lagnew2@une.edu.au
UNE Id une-id:lagnew2
Andronicos, Nicholas
( author )
OrcID: https://orcid.org/0000-0001-5881-2296
Email: nandroni@une.edu.au
UNE Id une-id:nandroni
Type of document
Journal Article
Language
en
Entity Type
Publication
Publisher
Walter de Gruyter GmbH
Place of publication
Germany
DOI
10.1515/revneuro-2016-0037
UNE publication id
une:22228
Abstract
Salivary cortisol may be used as a biomarker of stress and anxiety in children with an autism spectrum disorder (ASD). Some suggestions have been made that the measurement of cortisol needs to be undertaken by repeated days' observations to ensure reliability of the data obtained. These requirements are discussed in regard to 14 studies of the test-retest agreement and stability in cortisol data across repeated daily measurements. Results of those studies almost universally fail to support the argument for repeated daily measurements of cortisol. Implications for the research protocols of studies using cortisol as an index of stress in children with ASD are discussed.
Link
Citation
Reviews in the Neurosciences, 28(1), p. 103-111
ISSN
2191-0200
0334-1763
Start page
103
End page
111

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