Cancer Prevalence and Etiology in Wild and Captive Animals

Title
Cancer Prevalence and Etiology in Wild and Captive Animals
Publication Date
2017
Author(s)
Madsen, Thomas
Arnal, Audrey
Roche, Benjamin
Thomas, Frederic
Ujvari, Beata
Vittecoq, Marion
Bernex, Florence
Abadie, Jerome
Labrut, Sophie
Garcia, Deborah
Faugere, Dominique
Lemberger, Karin
Beckmann, Christa
( author )
OrcID: https://orcid.org/0000-0002-7904-7228
Email: cbeckman@une.edu.au
UNE Id une-id:cbeckman
Editor
Editor(s): Beata Ujvari, Benjamin Roche, Frederic Thomas
Type of document
Book Chapter
Language
en
Entity Type
Publication
Publisher
Academic Press
Place of publication
Amsterdam, Netherlands
Edition
1
DOI
10.1016/B978-0-12-804310-3.00002-8
UNE publication id
une:22200
Abstract
Despite the evolution of numerous natural cancer suppressor mechanisms (DeGregori, 2011 ), neoplasia has been recorded in most metazoans (Leroi et al., 2003). Although, a few exceptional species, such as the naked mole-rat (Heterocephalus glaber) and sharks have been claimed to be resistant to cancer (Finkelstein, 2005; Tian et al., 2013). Recent studies have, however, shown that even these species may develop cancer (Delaney et al., 2016; Finkelstein, 2005) strongly suggesting that the vast majority of multicellular organisms are indeed susceptible to cancer. The frequent occurrence of cancer in metazoans suggests that neoplasia, similar to pathogens/parasites, may have a significant negative impact on host fitness in the wild (Vittecoq et al., 2013). This is supported by a recent review of wildlife cancer by McAloose and Newton (2009) demonstrating that high prevalence of cancer in, for example, Tasmanian devils (Sarcophilus harrisii) and belugas (Delphinapterus leucas) resulted in concomitant significant increase in levels of mortality and reduction in fitness.
Link
Citation
Ecology and Evolution of Cancer, p. 11-46
ISBN
9780128043806
9780128043103
Start page
11
End page
46

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