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https://hdl.handle.net/1959.11/22010
Title: | Cancer Prevalence and Etiology in Wild and Captive Animals | Contributor(s): | Madsen, Thomas (author); Arnal, Audrey (author); Roche, Benjamin (author); Thomas, Frederic (author); Ujvari, Beata (author); Vittecoq, Marion (author); Bernex, Florence (author); Abadie, Jerome (author); Labrut, Sophie (author); Garcia, Deborah (author); Faugere, Dominique (author); Lemberger, Karin (author); Beckmann, Christa (author) | Publication Date: | 2017 | DOI: | 10.1016/B978-0-12-804310-3.00002-8 | Handle Link: | https://hdl.handle.net/1959.11/22010 | Abstract: | Despite the evolution of numerous natural cancer suppressor mechanisms (DeGregori, 2011 ), neoplasia has been recorded in most metazoans (Leroi et al., 2003). Although, a few exceptional species, such as the naked mole-rat (Heterocephalus glaber) and sharks have been claimed to be resistant to cancer (Finkelstein, 2005; Tian et al., 2013). Recent studies have, however, shown that even these species may develop cancer (Delaney et al., 2016; Finkelstein, 2005) strongly suggesting that the vast majority of multicellular organisms are indeed susceptible to cancer. The frequent occurrence of cancer in metazoans suggests that neoplasia, similar to pathogens/parasites, may have a significant negative impact on host fitness in the wild (Vittecoq et al., 2013). This is supported by a recent review of wildlife cancer by McAloose and Newton (2009) demonstrating that high prevalence of cancer in, for example, Tasmanian devils (Sarcophilus harrisii) and belugas (Delphinapterus leucas) resulted in concomitant significant increase in levels of mortality and reduction in fitness. | Publication Type: | Book Chapter | Source of Publication: | Ecology and Evolution of Cancer, p. 11-46 | Publisher: | Academic Press | Place of Publication: | Amsterdam, Netherlands | ISBN: | 9780128043806 9780128043103 |
Fields of Research (FoR) 2008: | 060808 Invertebrate Biology 060809 Vertebrate Biology 060899 Zoology not elsewhere classified |
Fields of Research (FoR) 2020: | 310913 Invertebrate biology 310914 Vertebrate biology |
Socio-Economic Objective (SEO) 2008: | 970106 Expanding Knowledge in the Biological Sciences | Socio-Economic Objective (SEO) 2020: | 280102 Expanding knowledge in the biological sciences | HERDC Category Description: | B1 Chapter in a Scholarly Book | Editor: | Editor(s): Beata Ujvari, Benjamin Roche, Frederic Thomas |
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Appears in Collections: | Book Chapter |
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