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https://hdl.handle.net/1959.11/21265
Title: | First Report of Hepatitis E Virus Circulation in Domestic Pigs in Nigeria | Contributor(s): | Owolodun, Olajide A (author); Gerber, Priscilla Freitas (author) ; Gimenez-Lirola, Luis G (author); Kwaga, Jacob K P (author); Opriessnig, Tanja (author) | Publication Date: | 2014 | Open Access: | Yes | DOI: | 10.4269/ajtmh.14-0144 | Handle Link: | https://hdl.handle.net/1959.11/21265 | Open Access Link: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183390 | Abstract: | Hepatitis E virus (HEV) is an important cause of acute hepatitis in humans. Zoonotic transmission between pigs and humans has been confirmed. Human HEV infection is common in Nigeria; however, characterization of HEV infection in other species was lacking. The objective of this study was to investigate HEV infection in Nigerian pigs. A total of 286 serum samples from six states in Nigeria were tested for presence of anti-HEV IgG. Ninety fecal samples from one of these states (Plateau State) were tested for presence of HEV RNA. The overall prevalence of anti-HEV IgG-positive or suspect-positive pigs was 55.6% (159 of 286) with regional prevalence rates ranging from 36% (9 of 25; Delta State) to 88% (22 of 25; Taraba State). The overall HEV RNA prevalence rate was 76.7% (69 of 90). All polymerase chain reaction-positive samples belonged to HEV genotype 3 based on sequencing. The results indicate that HEV genotype 3 infection is widespread in Nigerian pigs. | Publication Type: | Journal Article | Source of Publication: | American Journal of Tropical Medicine and Hygiene, 91(4), p. 699-704 | Publisher: | American Society of Tropical Medicine and Hygiene | Place of Publication: | United States of America | ISSN: | 1476-1645 0002-9637 |
Fields of Research (FoR) 2008: | 070704 Veterinary Epidemiology 070703 Veterinary Diagnosis and Diagnostics 070712 Veterinary Virology |
Fields of Research (FoR) 2020: | 300905 Veterinary epidemiology 300904 Veterinary diagnosis and diagnostics 300914 Veterinary virology |
Socio-Economic Objective (SEO) 2008: | 830308 Pigs | Socio-Economic Objective (SEO) 2020: | 100410 Pigs | Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal |
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Appears in Collections: | Journal Article |
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