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https://hdl.handle.net/1959.11/21254
Title: | Association of concurrent 'porcine circovirus' (PCV) 2a and 2b infection with PCV associated disease in vaccinated pigs | Contributor(s): | Gerber, Priscilla Freitas (author) ; Johnson, John (author); Shen, Huigang (author); Striegel, Dave (author); Xiao, Chao-Ting (author); Halbur, Patrick G (author); Opriessnig, Tanja (author) | Publication Date: | 2013 | DOI: | 10.1016/j.rvsc.2013.06.004 | Handle Link: | https://hdl.handle.net/1959.11/21254 | Abstract: | Investigations were performed to characterize porcine circovirus (PCV) 2 infection in 10. week old pigs from a case of apparent vaccine failure. Thirty serum samples were collected from affected or non-affected pigs and tested for anti-PCV2 antibodies and PCV2 DNA. To address potential PCV2 vaccine compliance issues, samples were tested for antibodies against baculovirus and 'Mycoplasma hyopneumoniae' antigens present in the PCV2 vaccine utilized in this herd. Both PCV2a and PCV2b DNA were detected in 76.6% (90% positive for PCV2a, 86.6% positive for PCV2b), anti-PCV2 IgG in 90%, anti-baculovirus IgG in 50%, and anti-'M. hyopneumoniae' IgG in 43.3% of the samples. Frequency of baculovirus and 'M. hyopneumoniae' seropositive pigs was significantly lower in affected pigs. The finding that only 50% of the pigs developed a detectable immune response to vaccination suggests poor vaccine compliance or efficacy. Concurrent PCV2a and PCV2b infection was common and may have resulted in enhanced PCV2 replication. | Publication Type: | Journal Article | Source of Publication: | Research in Veterinary Science, 95(2), p. 775-781 | Publisher: | Elsevier Ltd | Place of Publication: | United Kingdom | ISSN: | 1532-2661 0034-5288 |
Fields of Research (FoR) 2008: | 070706 Veterinary Medicine 070703 Veterinary Diagnosis and Diagnostics |
Fields of Research (FoR) 2020: | 300907 Veterinary medicine (excl. urology) 300904 Veterinary diagnosis and diagnostics |
Socio-Economic Objective (SEO) 2008: | 830308 Pigs | Socio-Economic Objective (SEO) 2020: | 100410 Pigs | Peer Reviewed: | Yes | HERDC Category Description: | C1 Refereed Article in a Scholarly Journal |
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Appears in Collections: | Journal Article |
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