Please use this identifier to cite or link to this item: https://hdl.handle.net/1959.11/21252
Title: Lack of antibody protection against 'Porcine circovirus' 2 and 'Porcine parvovirus' in naturally infected dams and their offspring
Contributor(s): Dias, A S (author); Gerber, Priscilla Freitas  (author)orcid ; Araujo, A S (author); Auler, P A (author); Gallinari, G C (author); Lobato, Z I P (author)
Publication Date: 2013
DOI: 10.1016/j.rvsc.2012.09.009
Handle Link: https://hdl.handle.net/1959.11/21252
Abstract: The aim of this study was to evaluate 'Porcine parvovirus' (PPV) and 'Porcine circovirus' 2 (PCV2) infection in dams and their offspring and the role of antibody protection on these infections. Sera were collected from gilts and sows by venipuncture and from umbilical cord of newborn pre-suckle piglets for the detection of PCV2 and PPV antibodies by immunoperoxidase monolayer and haemmaglutination inhibition assays, respectively. Gilts and sows sera were submitted to viral detection by PCR, as well as heart, lung, tonsil and lymph nodes samples from stillborn and mummified fetuses. High antibody titers before artificial insemination (AI) (>5.120 and >2.560 UHA for PCV2 and PPV, respectively), were found associated with viremia and fetal exposure for both PCV2 and PPV, respectively, in gilts and sows, regardless of pregnancy stage. These infections resulted in litters with mummified, stillborn, as well as seropositive and viable newborns. These findings bring new evidence about the lack of antibody protection against PCV2 and PPV infections in dams, indicating that more studies are necessary about the role of humoral response against both pathogens.
Publication Type: Journal Article
Source of Publication: Research in Veterinary Science, 94(2), p. 341-345
Publisher: Elsevier Ltd
Place of Publication: United Kingdom
ISSN: 1532-2661
0034-5288
Fields of Research (FoR) 2008: 070712 Veterinary Virology
070704 Veterinary Epidemiology
070706 Veterinary Medicine
Fields of Research (FoR) 2020: 300914 Veterinary virology
300905 Veterinary epidemiology
300907 Veterinary medicine (excl. urology)
Socio-Economic Objective (SEO) 2008: 830308 Pigs
Socio-Economic Objective (SEO) 2020: 100410 Pigs
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
Appears in Collections:Journal Article

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